血液病患者激素治疗后的血糖变化特点及意义  

The Significance and Characters of Steroid-induced Hyperglycemia in the Patient with Hematonosis

作　　者：林志美[1] 饶进[1] 殷莉[1] 李世云[1] 

机构地区：[1]成都大学附属医院,四川成都610081

出　　处：《中国医学创新》2013年第23期121-123,共3页Medical Innovation of China

摘　　要：目的:观察不同血糖基础的血液病患者使用糖皮质激素(GC)治疗前后的血糖变化特点,探讨其临床意义。方法:65例血液病患者按OGTT分组为糖调节正常(NGT)、糖耐量异常(IGT)和糖尿病(DM)三组,观察各组患者使用GC治疗前后的血糖变化特点。结果:GC治疗后所有患者日平均血糖升高,且餐后血糖升高明显,GC治疗后三组间三餐前后各点血糖值比较差异有统计学意义(P<0.05)。结论:GC治疗后大部分患者的血糖都会升高,且GC所致血糖变化具有其自身特点,大部分患者表现为午后至睡前严重高血糖,部分患者可出现夜间低血糖。Objective： To investigate the characteristics of daily blood glucose profiles of patients with Hematonosis with glucocorticoid （CG） therapy.Method： 65 patients with hematological diseases were divided into normal blood glucose group NGT （ normal glucose tolerance ）, IGT （ impaired glucose tolerance ） and DM （ diabetes mellitus ） three groups with OGTT, the blood glucose levels of patients were characterized using GC before and after treatment.Result： Average level of daily blood glucose was higher after GC therapy, especially postprandial blood glucose.The significant difference was found in average level of blood glucose in three groups after GC therapy （ P〈0.05 ） .Conclusion： After glucocorticoid treatment most of the patient＇s blood glucose will rise, and the change of glucocorticoid induced by glucose has its own characteristics, and most of the patients showed server hyperglycemia afternoon to bedtime, partial patient can appear nocturnal hypoglycemia.

关 键 词：糖皮质激素 类固醇糖尿病 血液病 高血糖 血糖波动 

分 类 号：R587.1[医药卫生—内分泌]