儿童青少年注意缺陷多动障碍共病双相障碍的行为特征研究  

Study on Behavior Characteristics of Attention Deficit Hyperactivity Disorder with Bipolar Disorder in Children and Adolescents

作　　者：程道猛[1] 苗国栋[1] 刘靖雯[1] 殷青云[1] 徐莉萍[1] 

机构地区：[1]广东省广州市精神病医院,广东广州510370

出　　处：《医学临床研究》2013年第7期1262-1263,1266,共3页Journal of Clinical Research

基　　金：广州市医药卫生科技项目（2009-YB-220）

摘　　要：【目的】了解儿童及青少年注意缺陷多动障碍（ADHD）共病双相障碍（BD）的发生率其行为特点。【方法】对符合美国精神疾病诊断标准第四版（DSM—IV）ADHD诊断的患者按DSM—IV的BD诊断标准进行再诊断，并对单纯ADHD患者其进行1～2年的随访，评估新发生的BD；所有被试由家长填写Achenbach儿童行为量表（CBCL）进行行为评估。【结果】共收集ADHD惠儿112例，其中15例患者同时符合BD诊断，经过1～2年随访，又新发生8例BD。共收集到ADHD共患BD患儿23例，占20．5％；与单纯ADHD组相比，共患BD组的CBCL焦虑／抑郁、思维问题、违纪行为、攻击性行为、外化性行为及行为问题总分方面均明显升高，且两组相比较差异有显著性（P〈O．01）。【结论】ADHD与BD有较高的共病率，共病可导致在思维及违纪、攻击等外化性行为问题方面的损害，I临床上需引起足够重视。[Objective] To understand the prevalence rate and behavior characteristics of attention deficit hyperactivity disorder（ADHD） combined with bipolar disorder（BD） in children and adolescents. [Methods] According to the diagnostic criteria of BD in American mental disease diagnosis criteria IV （DSM-IV）, patients with ADHD accordance with DSM-IV were diagnosed again. Simple ADHD patients were followed up for 1- 2 years. The newly occurred BD was evaluated. The parents of all patients completed Achenbach child behav- ior checklist（CBCL）, and the behavior was assessed. [Results]A total of 112 ADHD patients were collected. Among them, 15 patients were accorded with the diagnosis of BD. After follow up for 1-2 years, BD oc- curred in 8 patients again. Totally 23 patients with ADHD and BD（20.5 %） were collected. Compared with simple ADHD, the scores of anxious/depression, thinking, delinquent behavior, aggressive behavior, exter- nalization and total scores of behavior problems in CBCL of ADHD combined with BD group obviously in- creased, and there were significant difference between two groups（ P 〈0.01）. [Conclusion]The prevalence rate of comorbidity of ADHD and BD is high. The comorbidity can cause the impairment of thinking and exter- nalization behavior problems such as delinquent and aggressive behavior. Therefore it should be paid more at- tention in clinical practice.

关 键 词：注意力缺陷障碍伴多动 

分 类 号：R725[医药卫生—儿科]