瞿麦等12味利水中药体外抗泌尿生殖道沙眼衣原体活性检测  

Inhibitory Activity of Diathus superbus L.and 11 Kinds of Diuretic Traditional Chinese Medicines for Urogenital Chlamydia Trachomatis in Vitro

作　　者：李建军[1] 涂裕英[1] 佟菊贞[1] 汪培土[2] 

机构地区：[1]中山医科大学附属第一医院,广东广州510080 [2]广东省武警总队医院,广东广州510507

出　　处：《中国中药杂志》2000年第10期628-630,共3页China Journal of Chinese Materia Medica

基　　金：卫生部科研基金中标课题!( 96 2 0 73 );中华医学会皮肤科学研究基金课题!( 1997 10 3 )

摘　　要：目的 :了解常用利水中药体外抗泌尿生殖道沙眼衣原体的活性。方法 :应用微量McCoy细胞培养法 ,检测了 12味利水中药体外抗衣原体的活性。结果 :瞿麦等 12味中药体外均有不同程度的抗泌尿生殖道沙眼衣原体的活性 ,其MICs值从 0 .12 2～ 6 2 .5mg·ml-1,瞿麦、茯苓皮、猪苓、茵陈的抗衣原体活性较强。并发现 :随着中药浓度的升高 ,衣原体包涵体的体积和数量逐渐减小、减少 ,最后消失 ;未发现这 12味利水中药对McCoy细胞的生长有明显影响和细胞毒作用。结论 :瞿麦等 12味利水中药体外均有一定抗泌尿生殖道沙眼衣原体的作用。Objective:To detect the susceptibility of urogenital chlamydia trachomatis(CT)to 12 kinds of diuretic traditional Chinese medicines.Methods:The inhibitory activity of these medicines for CT was detected by microculture technique of McCoy cell in vitro.Results:All the 12 kinds of diuretic traditional Chinese medicines had inhibitory activities for urogenital CT,with minimal inhibitory concentrations (MICs) from 0.122 mg·ml -1 to 62.5 mg·ml -1 .The activities of Diathus superbus L.,Poria cocos(Shcw.)Woft,Polyporus umbellatus and Artemissia capillaris were stronger.The number and volume of CT inclusions reduced gradually and disappeared finally with the rise of concentration.Conclusions:All the 12 kinds of diuretic traditional Chinese medicines possess some inhibitory activity for urogenital CT. [

关 键 词：利水中药 沙眼衣原体 非淋菌性尿道炎 药敏试验 

分 类 号：R285[医药卫生—中药学]