免疫1号方联合HAART对HIV/AIDS患者免疫功能重建的干预研究  

Intervention of Immune 1 combined HAART on immune function in patients with HIV/AIDS reconstruction

作　　者：吴欣芳[1] 王阶[1] 李勇[1] 

机构地区：[1]中国中医科学院广安门医院,北京100053

出　　处：《中国中药杂志》2013年第15期2453-2457,共5页China Journal of Chinese Materia Medica

基　　金：国家"艾滋病和病毒性肝炎等重大传染病防治"科技重大专项(2008ZX10005-004)

摘　　要：目的:观察免疫1号方联合HAART对HIV/AIDS患者免疫功能重建的影响。方法:符合纳入标准的HIV/AIDS患者228例,随机分为治疗组及对照组,每组各114例,治疗组给予免疫1号方联合HAART治疗,对照组给予免疫1号方安慰剂联合HAART治疗,于疗后评价2组患者治疗后CD4+T细胞计数的变化及其免疫重建有效率。结果:对于CD4+T细胞在200～350个/μL的患者,治疗组免疫重建有效率优于对照组。结论:免疫1号方联合HAART可显著促进部分HIV/AIDS患者(CD4+T细胞基线在200～350个/μL)的免疫重建,其毒副作用小,临床应用较为安全。Objective： To observe the effect of combination of Immune 1 and HAART on the CD4＋T cell count and its immune reconstitution rate. Method： Two hundred and twenty eight HIV/AIDS patients were randomly divided into treatment group and control group, patients from treatment group received Immune 1 combined HAART therapy, patients from control group was given placebo combined HAART and evaluate the change of CD4＋T cell count and its immune reconstitution rate. Result： In patients with CD4＋T cells baseline level （200-350 cell·μL-1）, Immune reconstitution rate of treatment group is significantly higher than the control group. Conclusion： Immune 1 combined HAART can effectively promote the immune reconstitution of patients with high CD4＋T cells baseline level（200-350 cell·μL-1） and show little side effect and is safe to treat HIV/AIDS disease.keywords：Immune 1

关 键 词：免疫1号方 HAART HIV AIDS CD4+T细胞 免疫重建 

分 类 号：R512.91[医药卫生—内科学]