厦门地区女性不孕患者860例免疫性不孕抗体检测结果分析  

Analysis on test outcomes of immune infertility antibodies in 860 female patients with infertility in Xiamen Area

作　　者：马莉[1] 马芳芳[1] 王厚照[1] 刘青[1] 田艳[1] 

机构地区：[1]解放军第174医院检验科,福建厦门361003

出　　处：《临床军医杂志》2013年第8期829-830,共2页Clinical Journal of Medical Officers

摘　　要：目的探讨抗精子抗体(ASAb)、抗卵巢抗体(AOAb)、抗子宫内膜抗体(AEAb)和抗心磷脂抗体(ACLAb)与女性不孕的关系。方法采用酶联免疫吸附实验ELISA和化学发光法对860例女性不孕患者和780例有生育史妇女进行4种血清免疫性抗体检测。结果女性不孕患者ASAb阳性率为10.70%,ACLAb阳性率为7.56%,AEAb阳性率为9.53%,AOAb阳性率为5.93%,4种抗体的阳性率明显高于对照组(P<0.05)。结论血清免疫不孕抗体与女性不孕密切相关,对免疫性不孕的诊断和治疗具有重要的指导意义。Objective To explore the relationship between female infertility and immune infertility antibodies such as anti-sperm antibody （ ASAb）, anti-ovary antibody （ AOAb ）, anti-edometrial antibody （ AEAb ） and anti-cardiolipin antibody （ACLAb）. Methods Enzyme linked immunosorbent assay （ELISA） and chemiluminoimmunoassay were used to determine the levels of the four kinds of serum immune infertility antibodies in 860 female patients with infertility and in 780 women with childbearing history as controls. Results The serum positive rates of ASAb, ACLAb, AEAb and AOAb were respectively 10.70% , 7.56% , 9.53% and 5.93 % in the female patients with infertility, significantly higher than that of the controls （ P 〈 0.05 ）. Conclusion Immune infertility antibodies are closely associated with female infertility and may provide important reference to its diagnosis and treatment.

关 键 词：不孕症 不孕抗体 女性 

分 类 号：R711.6[医药卫生—妇产科学]