棕榈花蕾水提物对雌兔激素水平的影响  

Effects of aqueous extract of Trachycarpus fortunei on hormone level in female rabbits

作　　者：齐汝霞[1,2] 张鹏[2] 姚晓红[3] 王传功[2] 李卫平[1] 

机构地区：[1]安徽医科大学基础学院,安徽合肥230032 [2]济宁医学院基础学院,山东济宁272067 [3]济宁第一人民医院,山东济宁272000

出　　处：《药物评价研究》2013年第4期274-276,共3页Drug Evaluation Research

摘　　要：目的通过棕榈花蕾水提物对雌性家兔体内激素水平的影响,进一步探讨其抗生育作用机制。方法给健康雌性未孕家兔ip不同剂量的棕榈花蕾水提物,每天1次,连续9d。给药后分别从耳动脉取血,测定血清中的FT3、FT4、雌二醇、孕酮。结果与生理盐水组相比,棕榈花蕾水提物高剂量组明显降低家兔血清中FT3水平、升高孕酮含量,而各剂量组对FT4和雌二醇含量无明显影响。结论棕榈花蕾水提物能降低家兔血清中FT3水平,并升高孕酮含量。Objective To explore antifertility effects by the influence of Trachycarpusfortunei on hormone level in female rabbits. Methods To test the level ofestradiol, progesterone and thyroid hormone by Elecsys 2010 after intraperitoneal injection of palm buds. Results FT3 was reduced and progesterone was increased obviously by high dose of AEPB. Three doses of AEPB have no effects on FT4 and estradiol. Conclusion Aqueous extract of palm buds have the effects of reducing FT3 and increasing progesterone.

关 键 词：棕榈 雌性家兔 FT3 FT4 雌二醇 孕酮 

分 类 号：R979.21[医药卫生—药品]