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作 者:阎妍[1]
机构地区:[1]天津中新药业集团股份有限公司,天津300193
出 处:《药物评价研究》2013年第4期311-314,共4页Drug Evaluation Research
摘 要:川芎、当归是已知作用较强的活血化瘀中药,由其组成的复方芎归滴丸(舒脑欣滴丸)能增加实验动物的脑血流量、降低血黏度、保护心脏、预防急性脑梗死、抑制海马神经元缺氧损伤,还能下调脑干c-fos基因mRNA的表达,可以用于治疗缺血性脑血管病、偏头痛、血管性老年痴呆等,具有广阔的临床应用前景。Chuanxiong Rhizoma and Angelica Sinensis Radix are known as blood circulation drugs with relatively strong pharmacological effects. Xionggui Dripping Pills (Shunaoxin Dripping Pills) which are composed of Chuanxiong Rhizoma and Angelica Sinensis Radix are able to increase the cerebral blood flow of experimental animals, reduce blood viscosity, protect the heart, prevent acute cerebral infarction, inhibit hippocampal neurons hypoxic injury, and down-regulate c-fos gene mRNA expression. Therefore, the medicine can be used in the treatment of ischemic cerebrovascular disease, hemicrania, vascular dementia,which has the broad clinical application prospects.
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