Palladium-Catalyzed Cross-Coupling of Fluorinated Vinyl Chlorides with Terminal Alkynes： A General Protocol to Fluorinated Enynes  

作　　者：Sheng Chen Chunfa Xu Long Lu Qilong Shen 

机构地区：[1]Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2013年第7期901-907,共7页中国化学（英文版）

基　　金：Acknowledgement The authors gratefully acknowledge the financial support from National Basic Research Program of China （Nos. 2012CB821600, 2010CB126103）, the Key Program of Natural Science Foundation of China （No.21032006）, National Natural Science Foundation of China （Nos. 21172245, 21172244, B020304）, Agroscientific Research in the Public Interest （No. 201103007）, the National Key Technologies R＆D Program （No. 2011BAE06B05）, Shanghai Scientific Research Program （No. 10XD1405200）, and SIOC.

摘　　要：An efficient and cost-effective method for the preparation of fluorinated conjugated enynes was described, tile method was compatible with a variety of functional groups such as chloride, amine, cyano and ester group. The method could also be extended to the coupling of （R,Z）-3-（2-chloro-1,2-difluorovinyl）-4-alkyloxazolidin-2-one （3） with moderate yields.An efficient and cost-effective method for the preparation of fluorinated conjugated enynes was described, tile method was compatible with a variety of functional groups such as chloride, amine, cyano and ester group. The method could also be extended to the coupling of （R,Z）-3-（2-chloro-1,2-difluorovinyl）-4-alkyloxazolidin-2-one （3） with moderate yields.

关 键 词：FLUORINE ENYNE PALLADIUM CHLOROTRIFLUOROETHYLENE 

分 类 号：O623.124[理学—有机化学] TQ153.15[理学—化学]