C反应蛋白和空腹血糖与急性冠脉综合征患者近期预后的相关性研究  

Correlational study on the effects of C reactive protein and fasting blood glucose to short-term outcomes in patients with acute coronary syndrome

作　　者：叶永刚[1] 蒋利[1] 王寅[1] 徐颖杰[1] 岳静雯[1] 

机构地区：[1]上海市长宁区中心医院心血管内科,上海200335

出　　处：《实用临床医药杂志》2013年第9期19-22,共4页Journal of Clinical Medicine in Practice

基　　金：上海市卫生局科技发展基金资助(054111)

摘　　要：目的研究C反应蛋白(CRP)和空腹血糖(FBG)对急性冠脉综合征(ACS)患者近期预后的影响。方法选取ACS患者623例,根据CRP检测结果和FBG检测结果分为4组:A组(FBG正常,CRP正常)、B组(FBG正常,CRP升高)、C组(FBG升高,CRP正常)及D组(FBG与CRP均升高)。观察患者1个月内主要心血管事件(MACE)的发生情况,并应用Logis-tic回归模型分析MACE危险因素。结果与A组相比,其他3组MACE发生率均显著增加。高年龄、高血压、血脂异常、FBG升高、CRP升高都是MACE的危险因素。结论 FBG升高及CRP水平升高与ACS患者近期主要心血管事件的发生呈正相关。二者都升高者,近期预后差。Objective To investigate the effects of C reactive protein（CRP） and fasting blood glucose（FBG） to short-term outcomes in patients with acute coronary syndrome（ACS）.Methods A total of 623 patients with ACS were divided into 4 groups： control group（normal FBG and normal CRP）,normal FBG and high level of CRP group,normal CRP and high level of FBG group,and high level of FBG and CRP group.Major adverse cardiac events（MACE）（including myocardial infarction,revascularization and cardiac death） in 1 month were compared between each group.Logistic regression model was used to evaluate the risk factors of MACE.Results Compared with the control group,the rate of MACE was higher in the other three groups.The age,hypertension,dyslipidemia,high level of FBG and CRP were risk factors for short-term MACE.Conclusion In ACS patients,FBG and CRP have positive correlation with MACE in short-time prognosis.Patients with increase of both factors have poor outcomes.

关 键 词：急性冠脉综合征 空腹血糖 C反应蛋白 心血管事件 近期预后 

分 类 号：R541[医药卫生—心血管疾病]