影响早产儿脑血流动力学变化因素分析  

Analysis of factors affecting changes in cerebral blood flow of preterm infants

作　　者：安晶慧[1] 杨永艳 

机构地区：[1]辽宁省沈阳市妇婴医院,辽宁沈阳110011 [2]辽宁省沈阳市苏家屯区中西医结合医院,辽宁沈阳110015

出　　处：《实用临床医药杂志》2013年第14期121-123,共3页Journal of Clinical Medicine in Practice

摘　　要：目的应用多普勒超声仪检测早产儿脑血流变化,分析影响早产儿脑血流动力学变化的因素并评估其在预防早产儿脑损伤的应用价值。方法采用美国飞利浦多普勒彩色超声诊断仪动态测定早产儿的脑血流参数。结果病理因素(低血糖、红细胞增多症、窒息、高胆红素血症、颅内出血、应用机械通气)对早产儿脑血流有直接影响;红细胞增多症、窒息、高胆红素血症均可导致收缩期血流速度峰值(Vs)、舒张末期血流速度(Vd)降低,Vd降低更加明显,Vs与Vd的比值(S/D)升高,差异有统计学意义(P<0.05);阻力指数(RI)及搏动指数(PI)值增高,差异有统计学意义(P<0.05);低血糖、应用机械通气、颅内出血时Vs、Vd增高,RI及PI值降低,差异均有统计学意义(P均<0.05)。结论彩色多普勒超声动态检测早产儿脑血流动力学变化对预防和预测早产儿脑损伤有一定的临床诊断价值。Objective To analyze factors affecting changes of hemodynamics in preterm infants,assess their value in the prevention of brain injury in preterm children.Methods American Philips Doppler was used to diagnose dynamic cerebral blood flow parameters of the premature children.Results Pathological factors （hypoglycemia,polycythemia disease,asphyxia,hyperbilirubinemia,intracranial hemorrhage,the application of mechanical ventilation） affected cerebral hemodynamics preterm children.Polycythemia disease,asphyxia and hyperbilirubinemia could lead to peak systolic blood flow velocity （Vs）,diastolic velocity （Vd） reduce,Vd reduce more apparent elevated Vs and Vd ratio （S/D）,and the difference was statistically significant （P ＜ 0.05）.Resistance index （RI） and pulsatility index （PI） value increased,and the difference was statistically significant （P ＜ 0.05）.Hypoglycemia,mechanical ventilation,intracranial hemorrhage,Vs,Vd increased RI and PI values decrease,and the difference were statistically significant （P ＜ 0.05）.Conclusion Color Doppler ultrasound dynamically detect changes in cerebral hemodynamics in preterm children,which has a certain diagnostic clinical value of brain damage on the prevention of premature children.

关 键 词：早产儿 彩色多普勒超声 脑损伤 血流动力学 

分 类 号：R331[医药卫生—人体生理学]