对中药复方药代动力学研究中血药浓度测定方法的评述与思考  

Comment on the test method of plasma concentration in Pharmacokinectics of Chines herbal compound

作　　者：卢弘[1] 李敏[1] 邢东明[2] 杜力军[2] 

机构地区：[1]中国医学科学院中国协和医科大学药用植物研究所 [2]清华大学生物科学与技术系药理学实验室

出　　处：《世界科学技术-中药现代化》2000年第4期22-25,58,共4页World Science and Technology(Modernization of Traditional Chinese Medicine)

摘　　要：通过对有关文献及作者研究工作等分析思考，提出中药复方药代动力学研究中血药浓度测定占有十分重要的位置。血药浓度分析不在于测试成分的多少，而在于所测成分在多大程度上代表了所研究的复方。因此在进行血药浓度测定前，对所测成分进行认真慎重的选择是非常必要的。This paper argued that plasma concentration assay is important in the pharmacokinectic studies of Chinese herbal compound by means of analyzing their own previous work and related references. The application of plasma concentration test is proper or not, according as it represent the character of compound prescription of TCM, without reference to the amount of its detection. So it is of much necessity to determine carefully which constituent should be tested.

关 键 词：中药复方 药物代谢动力学 血药浓度 测定方法 

分 类 号：R285[医药卫生—中药学]