马鞭草环烯醚萜苷类成分的研究  

Studies on Iridoid Glucosides from Verbena officinalis

作　　者：张涛 阮金兰[2] 吕子敏 

机构地区：[1]武汉市职工医学院,430016 [2]同济医科大学药学院

出　　处：《中草药》2000年第10期721-723,共3页Chinese Traditional and Herbal Drugs

摘　　要：目的 :探索马鞭草抗早孕有效成分。方法 :甲醇渗漉提取 ,反复硅胶柱层析分离 ,理化常数和光谱分析鉴定化合物结构。结果 :从马鞭草甲醇提取物中分离并鉴定了 3个环烯醚萜苷 ,分别为马鞭草苷 ( )、3,4-二氢马鞭草苷 ( )和 5 -羟基马鞭草苷 ( )。结论 :其中 为新的天然化合物。For the purpose to seek the active components in the aerial parts of Verbena officinalis L with anti early pregnancy activity, the methanolic extract of this drug was repeatedly chromatographed on silica gel column Three iridoid glucosides were isolated and identified on the basis of physical, chemical evidences and spectroscopic analysis (UV, IR, 1HNMR, 13 CNMR, 1H 1HCOSY, 1H 13 CCOSY and DEPT) as verbenalin (Ⅰ), 3, 4 dihydroverbenalin (Ⅱ) and hastatoside (Ⅲ) Ⅱ is a new natural compound

关 键 词：马鞭草 环烯醚萜苷 3 4-二氢马鞭草苷 

分 类 号：R284.1[医药卫生—中药学]