悬浮芯片技术对3种常规病原体检测的敏感性和特异性的判定  

Sensitivity and specificity of suspension array technology in detection of 3 kinds of conventional pathogens

作　　者：陆青云[1] 陈峰[2] 吴尔翔[2] 丁锁顺[2] 邵亚平[2] 周敏[3] 

机构地区：[1]南通大学,江苏南通226019 [2]南通出入境检验检疫局,江苏南通226005 [3]南通市疾病预防控制中心,江苏南通226007

出　　处：《中国卫生检验杂志》2013年第8期1922-1923,1962,共3页Chinese Journal of Health Laboratory Technology

基　　金：江苏卫生厅预防医学科研项目(Y201038)

摘　　要：目的:比较悬浮芯片技术对3种常规病原体乙肝、丙肝、梅毒检测的敏感性和特异性。方法:选取2010年3月-2012年3月间在本中心接受的疑似常规病原体乙肝、丙肝、梅毒感染的患者(各200例)为研究对象,通过悬浮芯片技术对病原体进行检测,追踪他们最终的确诊情况,用SPSS软件分析比较检查结果的符合情况、检出率。结果:悬浮芯片技术对乙肝的敏感性最高;对乙肝、丙肝和梅毒螺旋体的检出特异性方面,组间差异性没有统计学意义。结论:悬浮芯片技术对乙肝敏感性优于丙肝和梅毒螺旋体,对三者的特异性相同。Objective： To compare the sensitivity and specificity of the suspension array technology on three con- ventional pathogens such as hepatitis B, hepatitis C and syphilis. Methods： The patients with hepatitis B, hepatitis C or syphilis （n = 200 respectively） in Nantong Center for Disease Control and Prevention during March 2010 and March 2012 were collected to detect the corresponding pathogens in serum by suspension array technology, and trace their final confirmed diagnosis. Then the inspection results were compared by SPSS software for statistical analysis. Results ： The suspension array technology had the highest sensitivity in the hepatitis B detection, and had no statisti- cal significance in specificity difference of detection of hepatitis B, hepatitis C and syphilis. Conclusion ： The sensi- tivity of suspension array technology on hepatitis B virus is superior to the hepatitis C virus and treponema pallidum, which has the same specificity to the three.

关 键 词：悬浮芯片技术 常规病原体 敏感性 特异性 

分 类 号：R446.5[医药卫生—诊断学]