2009年-2012年武威市流感监测病原学结果分析  

Analysis of influenza etiology surveillance results in Wuwei from 2009 to 2012

作　　者：王兴国[1] 周开春[1] 周斌[1] 

机构地区：[1]武威市疾病预防控制中心,甘肃武威733000

出　　处：《中国卫生检验杂志》2013年第8期1956-1958,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的：对2009年-2012年武威市流感监测结果进行分析，为武威市的流感防控工作提供科学依据。方法：武威市人民医院采集流感样病例的咽拭子标本，以荧光定量PCR方法检测病毒核酸，并对流感病毒感染情况进行流行病学分析。结果：共采集流感样病例咽拭子1944份，检测出流感核酸阳性标本367例，检出率为18．88％，其中新甲型H1N1127份，季节性流感H390份，季节性流感H11份，流感B型95份，A未分型54份。按年度分析，2009年-2012年流感病毒检出率依次为29．87％、10．47％、8．05％和28．19％，按年龄组分析，小于1岁婴儿检出率最低为3．97％，显著低于与其它年龄组；15岁～20岁最高为33．57％。2011年-2012年用MDCK分离到43株流感病毒。结论：武威市2009年以新甲型H1N1流感流行为主，2010年-2011年流感活动很弱，仅为散发，2012年春季以B型为主，11月开始以季节性流感H3为主。流感流行每年均有一个高峰，是冬春季儿童常见的传染病。Objective： To analyze the epidemic characteristics of influenza from 2009 to 2012, and provide the scientific basis for prevention and control of influenza in Wuwei. Methods： The throat swab specimens of influenza - like illness were colleted from Wuwei People＇ s Hospital for virus nucleic acid detection by fluorescent quantitative PCR and epidemiological analysis. Results： In total 1944 specimens, there were 367 samples with influenza virus positive （ 18.88% ）, including 127 influenza A （ H1 N1 ） cases, 90 seasonal H3 N2 cases, 1 seasonal H1 N1 case, 95 influenza B cases, and 54 non- typed cases. From 2009 to 2012, the positive rates of ILl cases were 29.87%, 10.47% , 8.05% and 28.19% respectively. Infants under one year old had the lowest detection rate（3.97% ）, while the young between 15 and 20 years old had the highest detection rate （33.57%）. Conclusion： In Wuwei city, the new influenza A （H1N1） was dominant in 2009, while only sporadic influenza illness were found from 2010 to 2011. In 2012, the influenza B was dominant in spring, but seasonal H3 ranked the top from November. The in- fluenza peak can be found once in each year, popular in children in spring and winter.

关 键 词：流感病毒 监测 实时荧光定量PCR 

分 类 号：R511.7[医药卫生—内科学]