2010年淄博市疑似流行性乙型脑炎病例血清抗体检测结果分析  

Analysis of specific antibody detection results in suspected Japanese encephalitis patients in Zibo in 2010

作　　者：郭茜[1] 刘超[1] 管廷龙[1] 李蕾[1] 

机构地区：[1]淄博市疾病预防控制中心,山东淄博255026

出　　处：《中国卫生检验杂志》2013年第8期1975-1977,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:对淄博市疑似流行性乙型脑炎进行特异性抗体检测,为乙脑疫苗接种和乙脑的诊断、预防控制提供科学依据。方法:采用酶联免疫试验检测乙脑病毒IgM抗体。结果:检测标本398份,乙脑抗体阳性37人,阳性率为9.30%。淄博市大龄儿童和成人乙脑发病构成比不断增加,病例年龄分布逐渐向成人偏移。不同年龄阳性率差异有统计学意义(χ2=17.74,P=0.00).结论:淄博市广泛存在乙脑流行,IgM抗体检测对病例确诊和疫情判定有重要意义,乙脑疫苗接种是预防乙脑疫情最有效的途径,在抓好适龄儿童乙脑疫苗接种工作质量的同时,适时开展针对成人接种,可降低高危人群的易感危险。Objective： To detect the specific antibody in suspected Japanese encephalitis patients, so as to pro- vide a scientific basis for vaccination, diagnosis and prevention of JE. Methods ： IgM antibody of JE virus were de- tected by enzyme- linked immunosorbent assay （ELISA）. Results：A total of 398 specimens were detected, inclu- ding 37 JE antibody positive, the positive rate was 9.30%. JE incidence of older children and adults is increasing in Zibo city, the age distribution of cases gradually offset to the adult. Conclusion： JE has been found prevalent in Zi- bo, and IgM antibody detection is of great significance to the JE diagnosis and epidemic evaluation. JE vaccination is the most effective way to prevent JE epidemic. Timely vaccination on school age children and adults can reduce the risk of JE epidemic in high- risk population.

关 键 词：乙脑病毒 IGM抗体 成人乙脑 

分 类 号：R512.32[医药卫生—内科学]