北京市西城区2011年-2012年孕产妇风疹IgM抗体、IgG抗体水平调查  

Survey on rubella IgM and IgG levels in maternal women in Xicheng district of Beijing from 2011 to 2012

作　　者：崔京辉 张晶波 李达 王永全 

机构地区：[1]北京市西城区微生物检验科,北京100120

出　　处：《中国卫生检验杂志》2013年第8期1990-1992,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:通过对北京市西城区2011年7月-2012年7月间1000份产妇血清风疹IgM抗体、IgG抗体水平的调查,为控制风疹发病,完善风疹免疫策略,预防先天性风疹综合征(CRS)提供科学依据。方法:采用定量酶联免疫吸附试验(ELISA)对北京市西城区2011年-2012年采集的风疹血清标本进行风疹IgM抗体、IgG抗体检测。结果:2011年-2012年共检测血清标本1000份。其中,风疹IgG抗体阳性842份,阳性率为84.2%。各年龄组统计分析(χ2=33.211,P<0.001),差异有统计学意义,且随年龄增长,风疹抗体水平显著下降。风疹IgM抗体只有1份阳性。结论:对育龄期妇女加强接种风疹疫苗(或含有风疹疫苗的联合疫苗),提高育龄妇女风疹抗体水平,是现阶段控制CRS重要手段。Objective： Through the analysis of 1000 maternal serum rubella IgM antibody and IgG antibody from July 2011 to July 2012 in Xicheng District of Beijing city, to provide a scientific basis for reducing incidence of ru- bella, preventing CRS and improving the rubella immunization strategy. Methods： Serum specimens were collected to detect the rubella IgM, IgG antibody by using quantitative ELISA. Results： A total of 1000 samples were detec- ted from 2011 to 2012, in which the rubella IgG antibody positive was found in 842 samples （84.2%）. In each age group, the difference was statistically significant （X2 = 33. 211, P 〈 0. 001 ）, and rubella antibody levels decreased significantly with age. There is only 1 rubella IgM antibody positive. Conclusion： Rubella vaccine should be vacci- nated to childbearing - age women, so as to improve the rubella antibody level, which is the important means to con- trol CRS.

关 键 词：风疹 CRS IGM抗体 IGG抗体 

分 类 号：R511.2[医药卫生—内科学]