100例ICU老年患者肺部真菌感染的危险因素及临床疗效观察  

100 Cases the ICU in Elderly Patients with Pulmonary Fungal Infection Risk Factors and Clinical Observation

作　　者：周凯[1] 

机构地区：[1]泸州医学院附属医院急诊科,四川泸州646000

出　　处：《中国医药指南》2013年第23期424-425,共2页Guide of China Medicine

摘　　要：目的探讨ICU老年患者肺部真菌感染的危险因素以及抢先治疗对其预后的影响。方法筛选本院ICU中达到临床诊断PFI标准的老年患者100例。随机平均分为甲、乙两组。甲组给予伏立康唑,乙组确诊后开始抗真菌治疗。对两组患者进行APACHEⅡ评分。计算MODS发生率及病死率。结果危险因素包括应用广谱抗生素、原发复杂基础疾病等;甲组的MODS发生率、APACHEⅡ分值均明显低于乙组(P<0.05)、住院时间少于乙组(P<0.01)。结论抢先治疗ICU老年患者PFI可有效的改善预后,减少住院时间。Objective To explore the ICU elderly patients with risk factors of pulmonary fungal infections, as well as the first to treat their prognosis. Method February 2009 to May 2012, 100 cases of elderly patients reach the clinical diagnosis PFI standard hospital ICU. Were randomly divided into 1, 2 two groups. One group was treated with voriconazole antifungal therapy in the 2 groups after diagnosis. APACHE II score of the two groups of patients. Calculate the incidence of MODS and mortality. Results The risk factors include the application of broad-spectrum antibiotics, primary complex underlying disease; 1 group the incidence of MODS, APACHE 17 scores were significantly lower than group 2 （P〈0.05）, and the length of stay is less than group 2 （P 〈0.01）. Conclusion The first treatment oflCU elderly patients the PFI can effectively improve the prognosis and reduce hospitalization time.

关 键 词：老年患者 PIF 抢先治疗 目的治疗 

分 类 号：R563[医药卫生—呼吸系统]