CAPABILITY OF DNA-FUELED MOLECULAR MACHINE IN TUNING ASSOCIATION RATE OF DNA-FUNCTIONALIZED GOLD NANOPARTICLES  

作　　者：Ting-jie Song Hao-jun Liang 

机构地区：[1]CAS Key Laboratory of Soft Matter Chemistry, Hefei National Laboratory for Physical Sciences at the Microscale, Department of Polymer Science and Engineering, University of Science and Technology of China

出　　处：《Chinese Journal of Polymer Science》2013年第9期1183-1183,1184-1189,共7页高分子科学（英文版）

基　　金：supported by the National Natural Science Foundation of China (Nos. 20934004 and 91127046);the National Basic Research Program of China (NBRPC) (Nos. 2012CB821500 and 2010CB934500)

摘　　要：The capability of our newly developed DNA-machine-driven strategy in tuning the association rate of DNA- AuNPs was compared with that of linker-addition strategy which has potential practical applications in different fields. The new established strategy shows its superiority to the linker-addition strategy in tuning the association rate of DNA-AuNPs in both pre-incubation treatment and non-incubation treatment conditions since its two components （a complex and a catalyst- oligonucleotide） can be individually optimized to make the machine run at an optimal rate. This strategy will provide a more convenient and flexible option in designing an oligonucleotide detection system and building a complex and versatile device.The capability of our newly developed DNA-machine-driven strategy in tuning the association rate of DNA- AuNPs was compared with that of linker-addition strategy which has potential practical applications in different fields. The new established strategy shows its superiority to the linker-addition strategy in tuning the association rate of DNA-AuNPs in both pre-incubation treatment and non-incubation treatment conditions since its two components （a complex and a catalyst- oligonucleotide） can be individually optimized to make the machine run at an optimal rate. This strategy will provide a more convenient and flexible option in designing an oligonucleotide detection system and building a complex and versatile device.

关 键 词：Assembly DNA ENHANCING KINETICS Nanoparticle. 

分 类 号：O631.3[理学—高分子化学]