基于石墨烯/金纳米棒的甲硝唑电化学行为及其检测  

Electrochemical behavior and detection of metrodinazole based on graphene/gold nanorods

作　　者：白万乔[1,2] 黄华宇 郭睿[1] 张慧月[1] 杜利劳 张振文 

机构地区：[1]陕西科技大学化学与化工学院,西安710021 [2]陕西省环境科学研究院,西安710061

出　　处：《化工新型材料》2013年第8期120-122,共3页New Chemical Materials

基　　金：陕西省科技统筹创新工程计划专题(2011KTZB03-03-01-02)

摘　　要：碱性条件下制备水中分散性良好的石墨烯,并通过一步还原法得到石墨烯/AuNRs复合材料。利用滴涂法制备石墨烯/AuNRs修饰电极,并研究了甲硝唑在该修饰电极上的电化学行为。结果表明,在pH=7.4时,甲硝唑在修饰电极上出现明显的氧化还原峰。甲硝唑在该修饰电极的还原峰峰电流与浓度在3.0×10-7～5.0×10-5 mol/L(S/N=3)范围内呈良好的线性关系,检出限为9.2×10-8 mol/L。该检测方法具有良好的灵敏度、选择性和稳定性,可用于甲硝唑药物的分析。同时也展现了这种新型的复合纳米材料在药物的检测中的应用潜力。Well-dispersed water soluble graphene was developed under alkaline condition,and the composite material of graphene/AuNRs was prepared by one-step reduction method.The electrochemical behavior of metrodinazole was studied on the electrode modified with graphene/AuNRs by casting.The results indicated that there were well defined redox voltammetric peaks at the pH value of 7.4.The peak currents varied linearly with the concentration of metrodinazole over the range from 3.0×10-7~5.0×10-5mol/L,and the detection limit was 9.2×10-8mol/L（S /N= 3）.The detection method showed great sensitivity,selectivity and stability,and could be used for the analysis of metronidazole drugs.It also can been seen that the novel composite material had a great potential in detection of pharmaceuticals.

关 键 词：石墨烯 金纳米棒 电化学性能 甲硝唑 

分 类 号：TQ460.7[化学工程—制药化工] O657.1[理学—分析化学]