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机构地区:[1]北京中医药大学中药学院,北京100102 [2]中药基础与新药研究北京市重点实验室,北京100102 [3]新疆医科大学药学院,新疆乌鲁木齐830011
出 处:《中国中药杂志》2013年第16期2633-2638,共6页China Journal of Chinese Materia Medica
摘 要:金鸡菊属植物约有100种,主要分布于美洲、非洲南部及夏威夷群岛等地,其中我国常见的该属植物有7种。金鸡菊属植物两色金鸡菊Coreopsis tinctoria为我国维吾尔族民间草药雪菊的基原植物,《中华本草》名曰蛇目菊,具有清热解毒、化湿止痢之功效。金鸡菊属植物的化学成分主要为黄酮类、苯丙素类、倍半萜类、聚炔类及甾醇类,具有抗炎等多种活性。该文综述了金鸡菊属植物的化学成分和药理作用,并对其开发前景进行了展望,以期为该属植物的深入研究和开发利用提供参考。There are about 100 species in the genus Coreopsis which distributed in the America, south of Africa and Hawaiian Islands, and 7 species are distributed in China. The inflorescences of Coreopsis tinctoria Nutt. is the Uigur herb 'Snow chrysanthemum' which is named 'Shemuju' with the effects of heat-cleaning, detoxicating, dampness-dissipating and dysentery-curing in the Xinhua Herbal Scheme. The chemical constituents from Coreopsis plants mainly contain flavonoids, phenylpropanoids, sesquiterpenes, and ste- rols, which show anti-inflammatory activities in modern pharmaceutical research. This article presents an overview of the chemical con- stituents and pharmaceutical activities, prospects of development and exploitation of Coreopsis plants, hopefully to provide a basis for further research and development of Coreopsis plants.
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