热毒宁注射液联合更昔洛韦治疗儿童传染性单核细胞增多症疗效观察  

Clinical observation on Reduning injection and ganciclovir in treatment of children with infectious mononucleosis

作　　者：万琦[1] 鄢素琪[1] 邓玉萍[1] 汤建桥[1] 李红[1] 

机构地区：[1]武汉市妇女儿童医疗保健中心,湖北武汉430016

出　　处：《中国医院药学杂志》2013年第16期1349-1350,1354,共3页Chinese Journal of Hospital Pharmacy

摘　　要：目的:观察热毒宁注射液联合更昔洛韦治疗传染性单核细胞增多症的临床效果。方法:将91例传染性单核细胞增多症儿童随机分为治疗组和对照组,治疗组采用热毒宁注射液联合更昔洛韦治疗,对照组单纯给予更昔洛韦治疗,进行临床疗效对比观察。结果:治疗组的临床症状、体征消退,外周血异型淋巴细胞消失时间均明显少于对照组,差异有显著意义(P<0.01)。治疗组的总有效率为93.48%;对照组的总有效率为77.78%,疗效明显优于对照组,两组比较差异有显著性(P<0.05)。结论:热毒宁注射液联合更昔洛韦治疗儿童传染性单核细胞增多症可有效缩短治疗时间,疗效显著,作用安全,值得临床推广应用。OBJECTIVE To observe the clinical efficacy of Reduning injection and ganciclovir in treatment of children with infectious mononucleosis. METHODS 91 patients were randomly divided into the treatment group and the control group, the treatment group was treated with Reduning injection and ganciclovir,the control group was only treated with ganciclovir. The clinical efficacy of each group was analyzed. RESULTS The extinction times of clinical symptoms and signs subside, atypical lymphocytes and fever in treatment group were obviously less than those in control group, the clinical efficacy of the treatment group was significantly superior to the control group （P〈0. 01）. The total effective rate of the treatment group was 93.48%; the total effective rate of the control group was 77. 78%, there was significant difference between two groups （P〈0. 05）. CON- CLUSION Reduning injection combined with ganciclovir to treat children with infectious mononucleosis was safe and effective, which could effectively shorten the time of therapy and be worthy of clinical application.

关 键 词：热毒宁注射液 更昔洛韦 儿童 传染性单核细胞增多症 

分 类 号：R969[医药卫生—药理学]