2型糖尿病患者血中甲状旁腺高血压因子的研究  

Study on parathyroid hypertensive factor and non-insulin-dependent diabetes mellitus

作　　者：张世联[1] 王薇[1] 朱文萍[1] 胡晓东[1] 赵睿珊[1] 尹桂山[2] 

机构地区：[1]河北省医学科学院生化研究室,石家庄050021 [2]河北医科大学生化教研室

出　　处：《临床内科杂志》2000年第6期355-357,共3页Journal of Clinical Internal Medicine

摘　　要：目的　探讨 2型糖尿病患者血中是否存有甲状旁腺高血压因子 (PHF)活性异常及其与胰岛素抵抗的关系。方法　采用生物活性测定方法 ,检测 32例 2型糖尿病患者和 33名正常人血浆中 PHF活性。结果　 2型糖尿病患者血中平均 PHF活性显著高于对照组 ,但未能确定与胰岛素抵抗之间的关系。结论　部分 2型糖尿病患者血中存有异常高水平的 PHF,其作用机制有待进一步研究。Objective To study the PHF activity in patients with non-insulin-dependent diabetes mellitus and its relation with insulin resistance.Methods The activities of plasma PHF in of 32 NIDDM patients and 33 healthy controls were measured by bioassay.Results The mean PHF levels in 32 NIDDM patients were higher than those in healthy controls. The relationship between PHF activity and insulin resistance was not made certain.Conclusion Abnormal PHF activities exists in part of NIDDM patients and its mechanism should be studied continually. [

关 键 词：甲状旁腺高血压因子 胰岛素抵抗 2型糖尿病 

分 类 号：R587.1[医药卫生—内分泌]