Affirm非剥脱性点阵激光治疗激光术后色素减退临床疗效观察  

The use ofAffirm fractional photothermolysis for the treatment of hypopigmentation

作　　者：杨鹏[1] 麦跃[1] 孙林潮 李娟[1] 鲁东平[3] 

机构地区：[1]大连医科大学附属深圳阳光医院皮肤科,深圳518000 [2]广州美莱美容医院 [3]深圳市宝安区慢性病防治院

出　　处：《实用皮肤病学杂志》2013年第3期168-170,共3页Journal of Practical Dermatology

摘　　要：目的观察Affirm非剥脱性点阵激光治疗激光术后色素减退的临床疗效和安全性。方法选取18例激光术后色素减退的患者,采用Affirm非剥脱性点阵激光治疗,光斑14mm,1320nm波长能量6.0～8.0J/cm2,1440nm波长能量1～2J/cm2。每部位扫描3～4次,共治疗10次,每4周1次,术后严格防晒。每次由2名固定医师同时对每例患者色素减退恢复情况按5级分类进行评分并摄相。结果 18例患者经过10次治疗,16.7%患者色素恢复等级达到5级,27.8%患者色素恢复等级达到4级,33.3%患者色素恢复等级达到3级,16.7%患者色素恢复等级达到2级,5%患者色素恢复等级达到1级。每次治疗对色素恢复等级评分的平均值进行t检验,差异具有统计学意义(P<0.05)。结论 Affirm非剥脱性点阵激光治疗激光术后色素减退疗效确切,安全性高,无明显不良反应,为临床治疗色素减退提供一种新的治疗手段。Objective To evaluate the efficacy and safety of Affirm fractional photothermolysis for the treatment of Affirm fractional photothermolysis. Methods Eighteen patients （Fitzpatrick skin types Ⅲ-Ⅳ） with hypopigmentation were enrolled. The lesions were treated withAffirm fractional photothermolysis, spotsize 14 mm, 1440 nm fluence 6.0～8.0 J/cm^2 , 1320 nm fluence 1～2 J/cm^2 , 3～4 pass, ten treatment sessions were performed for each patient 4 weeks. Comparative photographs were taken using graded on a 5-point scale to identify the repigmentation of lesions. Side effects were recorded at each follow-up. Results Eighteen cases of hypopigmentation obtained different degree of improvement were treated by 10 times. According to the over-all evaluation by dermatologists, 16.7% of the hypopigmentation showed repigmentation of grade 5, 27.8% of grade 4, 33.3% of grade 3,16.7% of grade 2, 5% of grade 1 The therapeutic effect was rised as the therapy times added. Conclusion Affirm fractional laser is effective and safe in the treatment of hypopigmentation, the side effects is rare, without downtime almost, which deserves the clinical expansion.

关 键 词：激光 点阵 色素减退 治疗 

分 类 号：R758.4[医药卫生—皮肤病学与性病学]