鲑鱼降钙素对维持性血液透析患者血压的影响  

The Effect of Salmon Calcitonin on Blood Pressure in Patients with Maintenance Hemodialysis

作　　者：刘春秋[1] 李良志[1] 刘雷[1] 汤跃武[1] 史继红[1] 王军[1] 吴泽成[1] 何先红[1] 

机构地区：[1]重庆三峡中心医院肾内科,重庆404100

出　　处：《中国医药导刊》2013年第5期854-855,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:观察鲑鱼降钙素对维持性血液透析患者血压的影响。方法:选择长期维持血液透析慢性肾衰患者120例,按抽签方式随机分为对照组和治疗组,各60例,对照组按常规给予治疗药物,治疗组在对照组治疗基础上应用鲑鱼降钙素注射液,观察治疗前后血压、血iPTH水平的变化。结果:与对照组比较,治疗组舒张压、收缩压、血iPTH水平均显著下降(P<0.05),血压达标率显著提高(x2=4.48,P=0.034)。结论:维持性血液透析患者应用鲑鱼降钙素能降低血iPTH水平,有助于血压的控制。Objective：To observe the effect of salmon calcitonin on blood pressure in patients with maintenance hemodialysis.Methods：120 patients having long-term maintenance hemodialysis along with chronic renal failure were selected,and they were randomly divided into a control group（n=60） and a treatment group（n=60） by sortition.Patients in control group were treated according to conventional treatment drug.Based on the treatment in control group,salmon calcitonin injections were applied in the patients of treatment group.The changes of blood pressure and iPTH levels were observed before and after treatment.Results：Compared with the control group,diastolic blood pressure,systolic blood pressure and iPTH levels were significantly decreased in the treatment group（P0.05）,the rate of reaching the standard in blood pressure was significantly increased（x2=4.48,P=0.034）.Conclusion：The application of salmon calcitonin in maintenance hemodialysis patients can lower iPTH levels in blood and help to control blood pressure.

关 键 词：鲑鱼降钙素 维持性血液透析 血压 甲状旁腺功能亢进 

分 类 号：R459.5[医药卫生—治疗学]