住院患者多重耐药菌感染临床研究  

Investigation on the characteristics of multiple-drug resistant organism infection in inpatients

作　　者：陈萍[1] 刘丁[1] 方清永[1] 王政[1] 王豪[1] 成瑶[1] 南玲[1] 黄庆宁[1] 

机构地区：[1]第三军医大学大坪医院野战外科研究所重庆市医院感染控制中心,重庆400042

出　　处：《中国微生态学杂志》2013年第8期962-965,968,共5页Chinese Journal of Microecology

摘　　要：目的探讨住院患者多重耐药菌感染情况与病原学特点,为临床制定医院感染控制措施提供参考依据。方法对住院患者中的多重耐药菌感染及病原特点情况进行统计分析。结果住院患者多重耐药菌感染发生率为3.5%,主要为革兰阴性菌(71.5%),多重耐药菌居前7位的依次是大肠埃希菌、肺炎克雷伯菌、鲍曼不动杆菌、铜绿假单胞菌、凝固酶阴性葡萄球菌、肠球菌属、金黄色葡萄球菌等。多重耐药菌感染的患者主要来自于重症监护室、神经外科、呼吸内科等。多重耐药菌对选用的抗生素均有较高的耐药性。结论多重耐药菌耐药率普遍较高,临床医师应重视病原学检查及药敏监测,合理选择使用抗菌药物。Objective To investigate the characteristics of infections caused by multiple-drug resistant organisms （MDROs） and provide reference for control of hospital-acquired infection. Methods The characteristics of infected inpatients and resistance rate of MDROs were analyzed. Results Incidence of hospital-acquired infection in patients with MDRO infection was 3.5%. Most of the MDROs were Gram-negative bacteria （71.5%）. The top 7 MDROs were Escherichia coil, Klebsiella pneumoniae, Acinetobacter baunam- mii, Pseudomonas aeruginosa, Coagulase negative staphylococcus, Enterococcus species arid Staphylococcus aureus. The drug resistant bacteria were mainly from the intensive care unit, neurosurgery, and respiratory medicine departments.. The MDROs in patients with hospi- tal-acquired infection were resistant to common-used antimicrobial drugs. Conclusion The resistance rate of MDROs isolated from inpa- tients is relatively high. Clinicians should pay attention to etiological inspection and monitor the rate of drug resistance in order to select and use the antibiotics more reasonably.

关 键 词：医院感染 多重耐药 耐药性 

分 类 号：R378[医药卫生—病原生物学]