三种方法治疗新生儿脓疱疮的临床疗效比较  

Comparison among the clinical efficacies of neonatal impetigo treated by three methods

作　　者：张萍萍[1] 肖峰[2] 纪曼芬[1] 陈凯云[1] 

机构地区：[1]中山大学附属第三医院儿科,广州510630 [2]中山大学附属第三医院口腔科,广州510630

出　　处：《新医学》2013年第8期540-542,共3页Journal of New Medicine

摘　　要：目的比较不同方法治疗新生儿脓疱疮的临床疗效,为临床治疗新生儿脓疱疮提供用药指导。方法将96例患脓疱疮的新生儿随机分为3组:洁悠神长效抗菌材料(洁悠神)组、莫匹罗星组和炉甘石组。全部患儿均每日予1∶6 000高锰酸钾溶液沐浴1次,沐浴后开始用药,洁悠神组用洁悠神进行创面喷洒,莫匹罗星组采用莫匹罗星涂抹,炉甘石组予炉甘石洗剂外涂,每日3次,治疗5 d后评价疗效。结果洁悠神组、莫匹罗星组、炉甘石组治疗新生儿脓疱的总有效率分别为88%、91%、66%,洁悠神组和莫匹罗星组总有效率比较差异无统计学意义(P>0.017),炉甘石组治愈率明显低于其他两组(P<0.017)。莫匹罗星组外涂部位发生皮肤刺激症状6例,洁悠神组和炉甘石组未发现明显不良反应。结论洁悠神与莫匹罗星治疗新生儿脓疱疮疗效优于炉甘石,且洁悠神不良反应较少。Objective To compare the clinical efficacies of three methods for the treatment of neo- natal impetigo, provide a medication guide for the clinical treatment of neonatal impetigo. Methods Ninety- six newborns with impetigo were randomly divided into three groups, that was, a group of JUC （ a kind of long- acting antibacterial material ）, Bactroban group and calamine group. All the patients bathed once every day with 1： 6 000 potassium permanganate solution, then drugs were used, JUC group with Jieyoushen for wound spray, Bactroban group with Baetroban to smear, the calamine group with calamine lotion applied externally, clinical analysis were carried on after 5 days of treatment. Results The Total effective rates in JUS group, Bactroban group and calamine group were 88% , 91% and 66% , respectively. There were no significant differ- ence of the total effective rates betweent JUS group and Bactroban group （P 〉 0. 05 ）. And the total effective rate in calamine group was significantly lower than those in the other two groups （P 〈 0. 05 ）. Bactroban group treated area of skin irritation in 6 cases, JUC group and calamine group found no significant adverse reactions. Conclusions JUS and Bactroban are more effective than calamine in the treatment of neonatal impetigo. And adverse reactions of JUS are fewer than that of Bactroban.

关 键 词：新生儿 脓疱疮 治疗 

分 类 号：R473.75[医药卫生—护理学]