术前应用坦索罗辛对降低经尿道前列腺电切综合征的临床研究  

The clinical study of preoperative application of Tamsulosin to reduce transurethral resection syndrome

作　　者：侯铁汉[1] 刘宇[1] 姜华茂[2] 冯艳红[2] 李季勇[1] 

机构地区：[1]葫芦岛市中心医院,辽宁葫芦岛125001 [2]辽宁医学院附属第一医院,辽宁锦州121001

出　　处：《中国医学工程》2013年第8期3-4,8,共3页China Medical Engineering

基　　金：辽宁省高等学校优秀人才支持计划资助(LJQ2012072);辽宁省科学技术计划项目(2010225034)

摘　　要：目的评价术前应用坦索罗辛对经尿道前列腺电切综合征(TURS)的影响。并根据其机制,对药物控制TURS术中并发症及提高手术疗效提供依据。方法将1年内收集的明确诊断为良性前列腺增生症(BPH)并行TURS手术的78例病历,按手术前半年是否服系统服用坦索罗辛药物治疗分为两组,比较术中血钠值及术中出血量、国际前列腺症状评分(IPSS)等指标的变化。结果治疗组术中血钠值(136.6±6.1)mmol/L高于对照组(132.3±5.5)mmol/L,治疗组术后2周IPSSP评分(8.0±4.1)分低于对照组(9.8±3.7)分,术中失血量治疗组(165.6±93.0)mL低于对照组(206.9±79.5)mL。结论坦索罗辛在减少经尿道前列腺电切并发症的发生及改善疗效方面是有效的。[ Objective ] Evaluation of preoperative application of Tanzania Sorosin of transurethral resection syndrome CrURS） effect. And according to its mechanism, To provide the basis for drug complications in TURS control and improve the effect of operation. [ Methods ] The diagnosis 1 years collected for benign prostatic hyperplasia （BPH） of 78 cases of parallel operation of TURS, According to the operation during the first half of the year whether suit system taking tamsulosin drug treatment were divided into two groups, Compared between the two groups of the variety of indexing of blood sodium intraoperative value, Intraoperative bleeding and the International Prostate Symptom Score （IPSS）. [ Resluts ] blood sodium intraoperative value in the treatment group（136.6 ± 6.1）mmol/L is more than that of the control group （132.3 ± 5.5）mmol/L. IPSS score （8.0 ±4.1） of the treatment group is lower than that of the control group （9.8 ± 3.7） 2 weeks after operation. Intraoperative blood loss treatment group （165.6 ± 93） mL lower than that of the control group （206.9 ± 79.5） mL. [ Conclusion ] Tamsulosin is effective to avoid the occurrence of TURS and postoperative complications.

关 键 词：坦索罗辛 良性前列腺增生症 慢性前列腺炎 经尿道前列腺电切综合征 经尿道电切综合征 

分 类 号：R697.33[医药卫生—泌尿科学]