基于造影图像的能量场反投影合成冠脉三维重建  

Energy back-projection composition model for 3-D reconstruction of coronary arteries based on angiographic image

作　　者：丛伟建[1] 杨健[1] 刘越[1] 王涌天[1] 

机构地区：[1]北京理工大学光电学院,光电成像技术与系统教育部重点实验室,北京100081

出　　处：《中国科学：信息科学》2013年第8期947-963,共17页Scientia Sinica(Informationis)

基　　金：国家重点基础研究发展计划(批准号:2010CB732505);国家高新技术研究发展计划(批准号:2013AA010803);北京市优秀人才支持计划(批准号:2010D009011000004)资助项目

摘　　要：基于造影图像的血管三维重建技术对于心血管疾病的计算机辅助诊断具有重要的临床实用价值.本文针对两幅单平面冠脉造影图像,提出了一种能量场反投影合成冠脉三维重建方法.深入研究了X射线造影成像原理和非封闭参数曲线构建方法,基于透视投影模型将两幅造影图像中形变曲线所受的外部驱动能量场反投影到三维空间中实现合成.在外部形变驱动力和内部平滑力的共同作用下,三维参数曲线不断形变向合成能量场最小的方向演化.为获得高精度的重建结果,通过曲线匹配方法实现参数曲线上点对点的稠密匹配,然后使用集束调整方法实现投影参数和血管三维结构的非线性全局优化.为了验证算法的有效性,我们将本文提出的方法在仿真数据和真实造影图像上进行了一系列实验;同时对具有不同造影成像角度差的图像进行了重建精度比较.实验结果表明本文提出的方法非常有效和鲁棒,重建冠脉血管树在三维空间中的均方误差小于0.80mm.3-D reconstruction of coronary artery has important clinical value for diagnosis and interventional treatment of cardiovascular diseases. In this paper, a novel energy back-projection composition model (EBPCM) is developed for reconstructing coronary arteries from two angiographic images. First, the imaging principle of X-ray and open parameter curve model are studied in detail. Then, the external forces of the parameter curves in the two angiographic images are back-projected into 3-D space and composited. Under joint effects of external driving forces and internal smoothing forces, the parameter curve is evolving continuously in 3-D space towards the true vascular structure with minimum composited energy. In order to improve the reconstruction accuracy, curve alignment method is employed to find the point-to-point matching relationship in the two angiographic images. Based on the fine points matching, bundle adjustment is utilized to perform non-linear optimization of projection parameters and the vascular structures simultaneously. The proposed method is validated on both phantom data and real angiographic images and the reconstruction results are compared on images with different imaging angles. Experimental results show that the developed method is very effective and robust, which can obtain accurate reconstruction of coronary arteries with space RMS error less than 0.80 mm.

关 键 词：三维重建 形变模型 透视投影 

分 类 号：TP391.41[自动化与计算机技术—计算机应用技术]