腹腔肿瘤患者围术期输血细菌感染的多因素logistic分析  

Multivariate logistic analysis of perioperative blood transfusion bacterial infections in peritoneal cancer patients

作　　者：徐学新[1] 韩海心[1] 徐一方[1] 杨旭[1] 张金生[2] 

机构地区：[1]南阳市中心医院输血科,河南南阳473009 [2]河南中医学院第一附属医院内科,河南郑州450000

出　　处：《中华医院感染学杂志》2013年第16期3932-3934,共3页Chinese Journal of Nosocomiology

基　　金：中国博士后基金(20070410129)

摘　　要：目的探讨分析腹腔肿瘤患者围手术期输血与术后细菌感染之间所存在的关系,为临床该类患者预防感染发生提供可靠有效依据。方法选取医院收入治疗的112例腹腔肿瘤患者,根据是否感染分为感染组(18例)和未感染组(94例),通过单因素分析和多因素logistic分析法,分析围术期输血患者术后细菌感染的影响因素。结果 112例腹腔肿瘤患者患者中,术后细菌感染的有18例,感染率为16.1%;单因素分析显示,围术期输血患者术后感染16例,无输血患者仅感染2例;感染患者平均手术时间(243.2±82.7)min,无感染患者平均手术时间(175.6±56.3)min,两者比较差异有统计学意义(P<0.05);其他性别、年龄、病程、术前血红蛋白、白细胞、血清白蛋白、术中失血量、手术部位、肿瘤分期等指标在有无感染患者间差异均无统计学意义;经多因素logistic分析校正后发现,输血与未输血患者发生术后细菌感染的OR值为1.246(95%CI:1.147～1.354,P<0.05)。结论围术期输血是术后细菌感染的独立危险因素,在腹腔肿瘤患者术中应减少术中出血,以降低患者感染概率。OBJECTIVE To explore the relationship between the perioperative blood transfusion and the postoperative bacterial infections in the abdominal cancer patients so as to provide reliable basis for prevention of infections in patients with such disease.METHODS A total of 112cases of abdominal tumor patients were enrolled in the study and were divided into the infection group（18cases）and the non-infection group（94cases）according to the infection status,then the impact factors for the postoperative bacterial infections in the patients undergoing perioperative blood transfusion were explored through the univariate analysis and the multivariate logistic analysis.RESULTS Of 112cases of abdominal tumors patients,the postoperative bacterial infections occurred in 18cases with the infection rate of 16.1%;the univariate analysis showed that there were 16cases of perioperative blood transfusion patients with postoperative infections and 2cases of patients with infections who did not undergo blood transfusion.The average operation duration of the patients with infections was（243.2±82.7）min,the patients without infections（175.6±56.3）min,the difference between the two was significant（P0.05）;the difference in other indicators,including the gender,age,disease course,preoperative hemoglobin,white blood cells,serum albumin,intraoperative blood loss,surgical site,and tumor stage,was not significant;the multivariate logistic analysis indicated that the OR value of the patients with postoperative bacterial infections who underwent blood transfusion and those who did not was 1.248（95%CI：1.147～1.354,P0.05,P0.05）.CONCLUSION The perioperative blood transfusion is an independent risk factor for the postoperative bacterial infections,we should try to reduce the intraoperative blood loss of the abdominal tumor patients so as to reduce the incidence of infections.

关 键 词：围术期 输血 腹腔肿瘤 术后细菌感染 

分 类 号：R181.32[医药卫生—流行病学]