外科手术部位感染病原菌分布及耐药性调查  

Distribution and drug resistance of pathogens causing surgical site infections

作　　者：王玲 侯飞 崔伟锋[2] 

机构地区：[1]河南省鹤壁京立医院检验科,河南鹤壁458030 [2]河南省中医药研究院,河南郑州450004

出　　处：《中华医院感染学杂志》2013年第16期4067-4068,共2页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金(81273877)

摘　　要：目的研究外科术后手术部位感染病的病原菌的分布以及病原菌的耐药性,指导临床对于外科手术部位感染的预防和控制,减少术后并发症的发生。方法对2008年1月-2012年1月临床手术患者的病例进行调查,筛选外科手术部位感染病例进行统计并对病原菌培养,观察其对于多种抗菌药物的耐药性,并进行数据分析。结果统计数据表明,外科手术部位感染的并发症发生率为6.1%,其中呼吸道感染占54.0%,其余各类感染均约10.0%;对葡萄球菌属和肠球菌属进行药敏试验,两者均对呋喃妥因和万古霉素的敏感性较高,分别为100.0%、88.0%;对于喹奴普汀/达福普汀和利奈唑胺则各异。结论通过对于病原菌耐药性的检测,可有效地控制临床外科手术感染,并预防手术部位感染,减少术后并发症的发生率。OBJECTIVE To study the distribution and drug resistance of pathogens causing surgical site infections so as to guide the clinical prevention and control of surgical site infections and reduce the incidence of postoperative complications.METHODS The clinical cases who underwent surgery in recent years were enrolled in the study,and the cases with surgical site infections were screened out for the statistical analysis,the pathogens were cultured,then the drug resistance of the pathogens was observed.RESULTS The statistical data showed that the incidence of complication of surgical site infections was 6.1%,and the cases with respiratory tract infections accounted for 54.0%,the cases with other sites of infections accounted for 10.0%.The drug susceptibility testing showed that the drug susceptibility rate of Staphylococcus or Enterococci to both nitrofurantoin and vancomycin was 100.0%,vancomycin 88.0%;Staphylococcus and Enterococci varied in the drug susceptibility to kuinuputing/dalfopristin or linezolid.CONCLUSION The detection of drug resistance of pathogens can help to effectively control the clinical surgical site infections,prevent the surgical site infections and reduce the incidence of postoperative complications.

关 键 词：外科手术 手术部位感染 病原菌分布 耐药性 

分 类 号：R378[医药卫生—病原生物学]