Cyclodextrin-Based Porous Nanocapsules  

作　　者：Youqing Wang Baohang Han 

机构地区：[1]National Center for Nanoscience and Technology, Beijing 100190, China

出　　处：《Chinese Journal of Chemistry》2013年第5期569-576,共8页中国化学（英文版）

基　　金：The financial support of the National Science Foundation of China，the Ministry of Science and Technology of China (National Major Scientific Research Program,Grant No.2011CB932500) is acknowledged

摘　　要：Cyclodextrins （CDs） are regarded as one kind of the most important and promising macrocyclic oligosaccha- rides, which contain hydrophobic internal cavities capable of hosting various guest molecules. CDs are water-solu- ble, non-toxic, commercially available as well as low-cost. Because of these favorable characteristics, cyclodextrin chemistry has created a great number of interesting works covering different fields, in particular CD-based porous nanocapsules （CDPNCs）. Chemical cross-linking is an important way developed to prepare CDPNCs. CDPNCs can be obtained using different cross-linkers and preparation methods, such as homogeneous method, miniemulsion po- lymerization, and emulsion-solvent evaporation method. Because of cross-linking, a three-dimensional network is built which forms the porous structure in CDPNCs with the cavities of CDs. Attributed to the porous structure, CDPNCs exhibit excellent performances in encapsulation of targeted molecules and realization of controllable re- lease, indicating a promising prospect in applications such as drug delivery systems and environment protection.Cyclodextrins （CDs） are regarded as one kind of the most important and promising macrocyclic oligosaccha- rides, which contain hydrophobic internal cavities capable of hosting various guest molecules. CDs are water-solu- ble, non-toxic, commercially available as well as low-cost. Because of these favorable characteristics, cyclodextrin chemistry has created a great number of interesting works covering different fields, in particular CD-based porous nanocapsules （CDPNCs）. Chemical cross-linking is an important way developed to prepare CDPNCs. CDPNCs can be obtained using different cross-linkers and preparation methods, such as homogeneous method, miniemulsion po- lymerization, and emulsion-solvent evaporation method. Because of cross-linking, a three-dimensional network is built which forms the porous structure in CDPNCs with the cavities of CDs. Attributed to the porous structure, CDPNCs exhibit excellent performances in encapsulation of targeted molecules and realization of controllable re- lease, indicating a promising prospect in applications such as drug delivery systems and environment protection.

关 键 词：cyclodextrins NANOCAPSULES POROUS cross-linking 

分 类 号：TQ658.41[化学工程—精细化工] TB383[一般工业技术—材料科学与工程]