Foldamer-Derived Preorganized Bi- and Tri-zinc Porphyrin Tweezers for a Pentafluorobenzene-bearing Pyridine Guest： The Binding Pattern Study  

作　　者：Changzhi Li Xin Zhao Xiang Gao Quanrui Wang Zhanting Li 

机构地区：[1]Department of Chemistry, Fudan University, Shanghai 200433, China [2]ghanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2013年第5期582-588,共7页中国化学（英文版）

基　　金：This work is financially supported by the National Natural Science Foundation of China

摘　　要：By introducing two and three zinc porphyrin units to one side of hydrogen bonding-induced aromatic amide foldamers, two new molecular tweezers 1 and 2 have been prepared. To explore new possible binding patterns, a leucine-based pyridine ligand 3 that bears a pentafluorophenyl group has been prepared. UV-Vis and IH NMR ex- periments reveal that 1 and 2 favorably complex one or two molecules of 3. UV-Vis titration experiments show that the apparent association constants of the complexes of the zinc porphyrin units of the two receptors and 3 are con- siderably higher than that of the complex between a simple control zinc porphyrin and 3. In the presence of excess of 3, the left zinc porphyrin unit of 1 and 2 can bind one more molecule of 3, which is, however, stabilized only by the single Zn-N coordination.By introducing two and three zinc porphyrin units to one side of hydrogen bonding-induced aromatic amide foldamers, two new molecular tweezers 1 and 2 have been prepared. To explore new possible binding patterns, a leucine-based pyridine ligand 3 that bears a pentafluorophenyl group has been prepared. UV-Vis and IH NMR ex- periments reveal that 1 and 2 favorably complex one or two molecules of 3. UV-Vis titration experiments show that the apparent association constants of the complexes of the zinc porphyrin units of the two receptors and 3 are con- siderably higher than that of the complex between a simple control zinc porphyrin and 3. In the presence of excess of 3, the left zinc porphyrin unit of 1 and 2 can bind one more molecule of 3, which is, however, stabilized only by the single Zn-N coordination.

关 键 词：molecular recognition FOLDAMER hydrogen bonding coordination PORPHYRIN 

分 类 号：O627.23[理学—有机化学] TQ330.47[理学—化学]