机械通气患者下呼吸道感染和多器官功能衰竭与预后  

Lower Respiratory Tract Infection,Multiple System Organ Failure and Prognosis of the Patients Receiving Mechanical Ventilation

作　　者：李景吾[1] 陈潮钦[1] 王少彬[1] 李安庆 

机构地区：[1]汕头大学医学院第一附属医院,汕头515041

出　　处：《华西医学》2000年第3期309-311,共3页West China Medical Journal

摘　　要：目的 :探讨机械通气患者下呼吸道医院感染和器官功能衰竭 (MSOD)与预后的关系。方法 :将机械通气患者下呼吸道分泌物作细菌培养和耐药试验 ,并分析院内感染、MSOF和死亡病例。结果 :本组有 2 4例并发下呼吸道感染 (80 % )。分离出 72株病原菌 ,其中G-杆菌 5 4株 (75 % ) ,尤以铜绿假单孢菌为多 (5 9% )。 2 4例发生MSOF (80 % )。 16例患者死亡 (5 3 3% ) ,混合菌感染组和单一菌感染组分别有 11例和 5例死亡 (P =0 0 0 49) ,未感染组无 1例死亡。MSOF组有 16例死亡 ,单器官功能衰竭组无 1例死亡 (P =0 0 72 3)。结论 :下呼吸道感染和MSOF在机械通气患者中十分常见 ;而且这两者都是影响患者死亡的主要因素。此外 ,尚需注意机械通气在下呼吸道感染和MSOF发生中的作用。Objective:To investigate the relationship of lower respiratory tract infection,multiple system organ failure(MSOF)and prognosis of the patients receiving mechanical ventilation Method:The germ cultures of secretion samples were conducted that were obtained from lower respiratory tract of the patients and drug-resistance was tested by soeptor semi-autotest system The numbers of dead patients,patients infected with multiple germs and patients with MSOF statistically were analyzed Result:There were 24(80%)patients with lower respiratory tract infection,24(80%)patients with MSOF and 16(53 3%)dead patients 72 strains germs were separated and there were 54 strains G - bacilli(75%),and 43 strains pseudomonas aeruginoea(59%) There were 11 and 5 dead patients in mixed-bacillus-infection group and one-germ-infection group,respectively( P =0 0049),and non dead patient in noninfection group,and 16 dead patients in MSOF group and non in one organ failure group( P =0 0723) Conclusion:lower respiratory tract infection and MSOF were very common in the patients receiving mechanical ventilation and both of them might affect mortality of patient receiving mechanical ventilation and mechanical ventilation might play a role in the infection and MSOF [WT5”HZ]

关 键 词：机械通气 下呼吸道感染 多器官功能衰竭 预后 

分 类 号：R563[医药卫生—呼吸系统]