三冬茶抗氧化作用研究  

Studies on Antioxidation Effects of Trilex

作　　者：蒋建敏[1] 许实波[1] 江润祥[2] 

机构地区：[1]中山大学药学系,广东广州501275 [2]香港中文大学中医学院

出　　处：《中成药》2000年第9期639-642,共4页Chinese Traditional Patent Medicine

基　　金：香港中文大学中医学资助 ;香港工业署工业发展科的基金项目!项目编号为AF/32 3/97

摘　　要：目的 :以大鼠组织匀浆及心肌线粒体为材料研究三冬茶的抗氧化作用。方法 :组织匀浆或心肌线粒体与三冬茶37℃共浴或以硫酸亚铁 /半胱氨酸 (Fe2 +/Cys)激发产生丙二醛 (MDA)作为过氧化程度指标。结果 :10、30、90 μg/ml三冬茶可抑制温浴及Fe2 +/Cys激发的MDA产生。 结论 :三冬茶可以减少氧自由基对生物膜的破坏 。Objective: To study antioxiation effects of Trilex in tissue homogenates and myocardial mitochondria of rats. Methods: Samples of tissue homogenates or mitochondria were pretreated with Trilex, then added Fe 2+ /Cys at 37℃ for about 1 h to initiate lipid peroxidation. The generation of malondialdehyde (MDA) were measured on spectrophotometer. Results: Trilex (10, 30, 90 μg/ml) inhibited Fe 2+ /Cys initiated lipid peroxidation in homogenates of different tissues (heart, brain, liver, kidney) and in myocardial mitochondria of rats. Conclusion: Trilex had preventive action against lipid peroxidation.

关 键 词：三冬茶 脂质过氧化 线粒体 组织匀浆 中药 

分 类 号：R285.5[医药卫生—中药学]