机构地区:[1]上海中医药大学附属岳阳中西医结合医院高血压重点专科,上海200437
出 处:《辽宁中医杂志》2013年第9期1752-1754,共3页Liaoning Journal of Traditional Chinese Medicine
基 金:上海市自然科学基金项目(10ZR1431100);高血压重点专病专科
摘 要:目的:探讨原发性高血压(EH)患者颈动脉硬化分布特征及其与中医证型的相关性,为中西医结合防治靶器官损害提供一定依据。方法:采集EH患者血压、年龄、性别、身高、体重、相关病史、中医症状,结合四诊情况由一名中医内科主任医师及两名中医内科主治医师进行中医辨证,同时检测颈动脉超声,采用卡方检验、Logistic回归分析等进行统计分析。结果:(1)老年组显著高于非老年组(P<0.01);男性组与女性组组间无统计学差异(P>0.05);(2)四个常见高血压中医证型中颈动脉硬化分布均>70%;肝火亢盛型(82.40%)>阴阳两虚型(80.15%)>痰湿壅盛型(73.53%)>阴虚阳亢型(71.14%)。肝火亢盛型与阴虚阳亢型患者间的颈动脉硬化情况有统计学差异(P<0.05);夹瘀组与非夹瘀组间无统计学差异(P>0.05);夹痰组发生率高于非夹痰组(P<0.05);(3)对26个症状进行Logistic回归分析,入选的3个症状中,眩晕、耳鸣症状与颈动脉硬化呈正相关(P<0.05)。结论:各证型中高血压患者颈动脉硬化分布均>70%,肝火亢盛型患者颈动脉硬化发生率最高,老年患者及夹痰患者更易发生颈动脉硬化,有颈动脉硬化的高血压患者眩晕及耳鸣的症状更明显。Objective : To study the distributional characteristics of carotid atherosclerosis by essential hypertension patients and correlation of TCM syndrome types with carotid atherosclerosis. The purpose is to prevent and control integrated traditional Chinese and western medicine, providing certain target organs' damage. Methods : BP, age, sex, body height and weight, associated medical history and TCM symptoms were collected. TCM syndromes were differentiated by the four diagnostics by a Chinese medical direc-tor physician and two TCM physicians. Carotid ultrasound was detected at the same time. And then we analyzed the data by using factor analysis, Logistic regression analysis and so on. Results:( 1 )Non -elderly patients' group and elderly patients' group had significant statistics differences(P 〈0. 01 ). There was no statistics differences between men's group and women's group (P 〉 0. 05 ). 2. In four common TCM syndrome types, the distribution of carotid atherosclerosis were all more than 70%. Yang hyperac-tivity type (82.40%) 〉 Yin - Yang deficiency (80.15%) 〉 stagnation of phlegm - dampness type (73.53%) 〉 Yin deficiency Yang hyperactivity type (71.14%). The carotid atherosclerosis of Yang hyperactivity type and Yin deficiency Yang hyperactivity type had statistics differences( P 〈 0.05 ). There was no statistics differences between clip stasis group and non - clip stasis' group ( P 〉 O. 05 ). Clip phlegm's group and non - clip phlegm's group had statistical differences ( P 〈 0. 05 ). 3. By the Logistic regres-sion analysis, vertigo, tinnitus is positively correlated with carotid sclerosis ( P 〈 O. 05 ). Conclusion : In all kinds of common TCM syndrome types, the distribution of carotid atherosclerosis are all more than 70%. The patients of Yang hyperactivity type are more likely to have carotid atherosclerosis. The elderly patients and clip phlegm patients are easy to have carotid atherosclerosis. The oc- currence rate of th
分 类 号:R259.441[医药卫生—中西医结合]
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