基于数据挖掘的七情配伍“相恶药对”药性组合规律研究  

Study on the compatibility principle of opposite assistant drug pairs based on the data mining

作　　者：秦丹[1] 吴嘉瑞[1] 李海娜[1] 杨瑞[1] 张冰[1] 张晓朦[1] 顾浩[1] 王苹[1] 

机构地区：[1]北京中医药大学中药学院,100102

出　　处：《国际中医中药杂志》2013年第9期821-823,共3页International Journal of Traditional Chinese Medicine

基　　金：北京市中医药科技基金课题（项目编号：JJ-2010-70）;国家级大学生创新创业训练计划课题（项目编号：201210026058）;北京中医药大学科研创新团队项目资助（项目编号：NO.2011-CXTD-14）

摘　　要：目的探讨七情配伍中相恶药对的药性组合规律。方法在收集整理《本草纲目》中相恶药对的基础上，基于ACCESS平台构建数据库，进而应用数据挖掘软件EnterpdseMiner中的关联规则算法，分析相恶药对的药性组合规律。结果相恶药对的常用药性组合模式包括：温辛脾一寒苦大肠、温甘肺一寒苦肺、温辛脾一寒苦心、温甘脾一寒苦肺等。结论相恶药对两药之间的药性具有一定的相反性，这在一定程度上验证了相恶具有疗效制约作用。Objective To investigate the compatibility principle of opposite-assistant drug pairs which come from seven aspects in prescription compatibility. Methods Based on the Access database, the opposite-assistant drug pairs which were collected from Compendium of Materia Medica , were analyzed by Enterprise Miner with the association rules to get the compatibility principle. Results The combined modes that frequently used included ＂warm, pungent, spleen-cold, bitter, large intestine＂; ＇warm, sweet, lungs-cold, bitter, lung＂; ＂warm, pungent, spleen-cold, bitter, heart＂; ＂warm, sweet, spleen-cold, bitter, lung＂. Conclusion There was a certain relationship that mutually exclusive between the two opposite-assistant drug pairs, which can prove these drug pairs would reduce the efficacy of each other.

关 键 词：七情配伍 相恶 数据挖掘 中药药性 

分 类 号：R285.1[医药卫生—中药学]