妊娠高血压综合征患者血浆D-D与hs-CRP检测及意义  

Patients with pregnancy-induced hypertension syndrome with hs-CRP detection of plasma D-D and significance

作　　者：章小东[1] 郑穗瑾[1] 付文金[1] 曾见芬[1] 刘亮[1] 陈载鑫[1] 余曼荣[1] 谢岭平[1] 

机构地区：[1]广东医学院附属厚街医院检验中心,广东523945

出　　处：《中国伤残医学》2013年第8期78-79,共2页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的：探讨血浆D—D及高敏c反应蛋白（hs—CRP）在妊娠高血压综合征患者血清中的检测及意义。方法：选择2011年9月-2012年9月在我院住院妊高征患者50例，其中子痫前期15例，轻度子痫22例，重度子痫13例，同期妊娠晚期健康妇女30例作为对照组。以免疫比浊法检测血浆D—D及hs—CRP水平。结果：实验组血浆D—D、CRP水平均高于对照组（P〈0．01），轻度子痫、重度子痫患者血浆D—D及hs—CRP水平高于子痫前期患者（P〈0．05），重度子痫高于轻度子痫患者（P〈0．05）。CRP与D—D水平呈正相关，r=0．61，P〈0．01。结论：D—D、CRP均参与了妊娠高血压综合征的发病进程，二者在妊娠高血压综合征患者中明显升高，并与疾病严重程度呈正相关。Objective： To investigate the plasma levels of D - D and high sensitive C reactive protein （ hs - CRP） in the detection and significance of serum in patients with pregnancy - induced hypertension syndrome. Methods ： From 2011 September - 2012 year in September in our hospital 50 patients with PIH, 15 cases with mild preeclampsia, eclampsia in 22 cases, 13 cases of severe preeclampsia during late pregnancy,30 healthy women as control group. In the detection of plasma D - D and hs - immunoglobulin CRP level the turbidimetric method. Results： In the experimental group, plasma D - I）, CRP levels were higher than those in the control group （ P 〈 0.01 ）, mild preeclampsia, severe preeclampsia patients plasma levels of D - D and hs - CRP levels were higher in patients with preeclampsia, severe preeclampsia （ P 〈 0.05 ） is higher than that of patients with mild preeclampsia （ P 〈 0.05 ）. CRP was positively correlated with the level of D - D, r = 0.61, P 〈 0.01. Conclusion： D - D, CRP were involved in the pathogenesis of pregnancy induced hypertension syndrome, two in the syndrome in patients with pregnancy induced hypertension and increased significantly, and the disease severity was positively correlated with.

关 键 词：妊娠高血压综合征 D—D C反应蛋白 

分 类 号：R714.24[医药卫生—妇产科学]