含聚乙二醇的嵌段共聚物的合成及自组装研究进展  

Research progress of synthesis and self-assembly for poly(ethylene glycol)-containing block copolymers

作　　者：栗志广[1] 马晓燕[1] 常海[2] 陈智群[2] 

机构地区：[1]西北工业大学空间应用物理与化学教育部重点实验室和陕西省高分子科学与技术重点实验室,陕西西安710129 [2]西安近代化学研究所,陕西西安710065

出　　处：《化工进展》2013年第2期381-387,413,共8页Chemical Industry and Engineering Progress

基　　金：陕西省自然科学基金(2009JZ004);2011基础研究基金(JC201158)项目

摘　　要：综述了通过活性自由基聚合如原子转移自由基聚合(ATRP)、氮氧稳定自由基聚合(NMP)、可逆加成断裂链转移聚合(RAFT)等方法合成含聚乙二醇(PEG)的嵌段共聚物的研究进展,并对含PEG类嵌段共聚物在溶液中的自组装技术和在药物载体、介孔材料以及碳纳米管中的应用进行了归纳,指出含PEG的嵌段共聚物可以自组装成多种形貌,直接影响材料的性能和应用,所以这些结构有潜在的应用价值和应用前景,并且合成新的含PEG的嵌段共聚物和开发具有新型结构、形貌可控的自组装体以及新的应用领域是今后的一个热点问题,具有重要的科学研究意义和实际应用价值。Research progress of radical polymerization methods for block copolymers with poly（ethylene glycol） is reviewed in this paper, including ATRP （atom transfer radical polymerization）, NMP （nitroxide-mediated radical polymerization）, and RAFT （reversible addition-fragmentation chain transfer polymerization）. Meanwhile, self-assembly in solution and applications of PEG-containing block copolymers in drug carriers, mesoporous materials and carbon nanotubes are also summarized. PEG-containing block copolymers can self-assemble into a variety of morphology of structures, which will directly affect the performance and application of the materials, so these structures have potential value and application prospects. The synthesis of new PEG-containing block copolymers and development of new, morphology-controlled self-assembly structures and new applications will be a central issue in the future with important scientific significance and practical value.

关 键 词：聚乙二醇 嵌段共聚物 自由基聚合 自组装 

分 类 号：O633.11[理学—高分子化学]