二氧化硅负载高氯酸催化合成对称N,N＇-亚烷基双酰胺  

An Efficient Synthesis of Symmetrical N,N′-Alkylidene Bisamides Catalyzed by Silica Supported Perchloric Acid

作　　者：王宏社[1] 赵卫星[1] 

机构地区：[1]宝鸡文理学院化学化工学院陕西省植物化学重点实验室,宝鸡721013

出　　处：《有机化学》2013年第8期1822-1827,共6页Chinese Journal of Organic Chemistry

基　　金：陕西省教育厅科研计划(No.12JK0615);宝鸡文理学院重点(No.ZK1053)资助项目~~

摘　　要：以二氧化硅负载高氯酸(HClO4-SiO2)为催化剂,醛与酰胺发生缩合反应得到了一系列N,N′-亚烷基双酰胺.该法操作简便、反应时间短、产率高和催化剂可重复使用.An efficient approach to the synthesis of symmetrical N,N＇-alkylidine bisamides from various aldehydes and amides in the presence of silica supported perchloric acid （HClO4-SiO2） has been described. The advantages of this method are easy work-up, short reaction times, excellent yields and the catalyst exhibited remarkable reusable activity.

关 键 词：HClO4-SiO2 醛 酰胺 双酰胺 

分 类 号：O621.36[理学—有机化学]