正交试验优选丹参茎叶中丹参素和丹酚酸B的提取工艺研究  

Study on extraction of Danshensu and Salvianolic acid B orthogonal test in the stems and leaves of Salvia miltiorrhiza

作　　者：刁保忠[1] 靳维荣[1] 张文周[1] 

机构地区：[1]聊城市人民医院,聊城252000

出　　处：《中华中医药杂志》2013年第9期2717-2720,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：山东省科技发展计划项目(No.2011YD19020)~~

摘　　要：目的:探讨丹参茎叶中丹参素和丹酚酸B的提取工艺优化。方法:以丹参素和丹酚酸B含量作为研究指标,考察了提取次数、提取时间、溶剂量、浸泡时间对丹参茎叶中水溶性成分提取率的影响,并通过正交试验设计确定了其最佳提取工艺。结果:取丹参茎叶中粉加入10倍量的水,浸泡1.0h,提取0.5h/次,100℃下提取3次,是其最佳提取工艺。结论:该工艺稳定可靠,可为丹参茎叶中的水溶性成分的工业化提取提供科学依据。Objective： Studying of optimization of the extraction technology of Danshensu and Salvianolic acid B in Salvia miltiorrhiza stem. Methods： On the basis of Danshensu and Salvianolic acid B, the extraction times, extraction time, solvent volume, soak time on the stems and leaves of Salvia miltiorrhiza water-soluble component extraction were studied. Results： The best extraction process of the stems and leaves of Salvia miltiorrhiza powder was that： 10 times amount of water were added, and were soaked for 1.0h, and 3 times at 100℃, 0.5h/time were extracted. Conclusion： The process is stable and reliable, which can provide scientific basis for the extraction of stems and leaves of Salvia miltiorrhiza water-soluble constituents of industrialization

关 键 词：正交试验 丹参茎叶 丹参素 丹酚酸B 提取工艺 

分 类 号：R284[医药卫生—中药学]