抗高血压联合用药分析  

To explore the reasonable of several anti-hypertensire combination regimens

作　　者：马文祥[1] 

机构地区：[1]太仓市中医医院药剂科,215400

出　　处：《中国老年保健医学》2013年第4期60-61,共2页Chinese Journal of Geriatric Care

摘　　要：目的客观探究几种抗高血压联合用药方案的合理性。方法对我院2011年1月至2011年12月收治的并且采用联合用药方案的高血压患者200例,从用药方案、频率、治疗效果等方面进行综合评价。结果二联用药、三联用药的使用频率分别为67.50%,32.50%,平均治疗效果分别为88.89%,86.15%。二联用药中,ACEI+Ca2+拮抗剂、钙拮抗剂+β受体阻断剂、β受体阻断剂+ACEⅠ的使用频率分别为60%,34.07%,5.93%,平均疗效分别为93.83%,86.96%,50%。三联用药中,ACEⅠ+利尿药+Ca2+拮抗剂和β受体拮抗药+Ca2+拮抗药+ACEⅠ的使用频率分别为79.63%和33.85%,平均疗效分别为90.70%和77.27%。结论在高血压治疗中采用联合用药的方法效果较好,值得临床推广应用。Objective To objectively explore several anti-hypertensive combination regimens reasonable. Methods Results and combination regimens in patients with hypertension and 200 cases in our hospital from January 2011 to December 2011 were treated to a comprehensive evaluation from the regimen,frequency of treatment effects. Results Two associated medication,triple therapy the frequency of use were 67. 50% ,32. 50% ,and the average treatment effect were 88. 89% ,86. 15% . The bivalent medication,the ACE Ⅰ ＋ Ca2＋ antagonists,calcium antagonists ＋ β receptor blockers,β-blockers ＋ ACE Ⅰ use frequencies were 60% ,34. 07% ,5. 93% ,and the average efficacy of 93. 83% ,86. 96% ,50% . The triple medication,ACE Ⅰ ＋ diuretics ＋ Ca2＋ antagonists and β receptor antagonist ＋ Ca2＋ antagonistic drug ＋ ACE Ⅰ use frequencies were 79. 63% and 33. 85% ,the average efficacy of 90. 70% and 77. 27% ,respectively. Conclusion Better combination in the treatment of hypertension,worthy of clinical application.

关 键 词：抗高血压 联合用药 分析 

分 类 号：R96[医药卫生—药理学]