吸毒人员HCV感染危险因素的Logistic回归分析  

Logistic Regression Analysis of Risk Factors of Hepatitis C Virus among Drug Addicts

作　　者：戴继舫[1] 李丽娜[1] 杨玉兰[2] 张培[2] 

机构地区：[1]湖北省疾病预防控制中心,湖北武汉430079 [2]宜昌市疾病预防控制中心,湖北宜昌443003

出　　处：《中国社会医学杂志》2013年第4期244-247,共4页Chinese Journal of Social Medicine

基　　金：湖北省全球基金项目(HBCBD-U10)

摘　　要：目的了解美沙酮门诊吸毒人员丙肝病毒(Hepatitis C virus,HCV)感染流行情况及相关因素。方法基于社区美沙酮门诊吸毒人员的基线调查,收集宜昌市572名吸毒人员相关社会因素和HCV检测情况,进行单因素和多因素Logistic回归分析。结果 572名吸毒人员中,男446人(78.0%),女126人(22.0%),平均年龄37岁,平均吸毒年限13年,有过注射吸毒史的517人占90.4%,曾经共用过注射器的140人(24.5%);HCV感染情况经过检测,572人中HCV阳性498人,阳性率87.06%。单因素分析结合Logistic回归分析显示:婚姻状况、吸毒年限、是否注射毒品是HCV感染的主要危险因素。结论尽管湖北省吸毒人群HIV感染不高,但HCV感染率很高,两者传播方式有明显差异,应该加强吸毒人群的HCV感染防治。Objectives To explore the status and any associated factors of Hepatitis C virus （HCV） prevalence a- mong drug addicts in Hubei province. Methods A community based HCV prevalence study of intravenous drug us- ers （IDUs） was conducted in methadone clinics of Yichang city. Logistic regression analysis was carried out based on data of demographics and results of HCV serological tests. Results Among the 572 drug addicts, 446 （84%） were male, 126 （22.0%） were female. Their average age was 37 years old, while their median injection duration was 13 years. Most （90.4%） of them reported having a history of IDU. A quarter （24.5%） of them admitted that they had ever shared injection syringe. The positive rate of HCV antibodies was 87.1%. Married status, drug tak- ing duration and having a history of IDU were independent factors of HCV infection. Conclusions Despite low HIV prevalence among drug addict in Hubei province, HCV prevalence is high. The modes of transmission were differ ent between HIV and HCV, prevention and treatment of HCV should be strengthened for drug addicts.

关 键 词：丙肝病毒 静脉注射吸毒 LOGISTIC回归分析 危险因素 

分 类 号：R512.63[医药卫生—内科学]