术中应用甲基强的松龙对脊髓型颈椎病患者的临床效果观察  

Observation on Clinical Effect of Methylprednisolone on Patients with Cervical Spondilotic Myelopathy

作　　者：朱一鹏[1] 

机构地区：[1]山东省单县中心医院,山东单县274300

出　　处：《河北医学》2013年第10期1481-1483,共3页Hebei Medicine

摘　　要：目的:探讨对脊髓型颈椎病患者实施手术治疗过程中应用甲基强的松龙(MP)的临床效果。方法:选取脊髓型颈椎病患者80例,随机分为两组,其中对照组38例,观察组42例,使其有可比性。对照组患者常规进行手术;观察组患者在对照组基础上与术中应用甲基强的松龙。使用JOA评分对两组患者关节功能进行评价;使用ODOM分级对两组患者治疗效果进行评价。结果:经过治疗,两组患者术后3d、7d以及1个月、3个月JOA评分均有所提高,但观察组患者提高更为明显;采用ODOM分级对两组患者治疗效果进行评价,观察组患者治疗优秀率及优良率分别为19.05%和80.95%,明显高于对照组13.16%和44.74%的比例。上述比较差异明显,有统计学意义(P<0.05)。结论:对脊髓型颈椎病前路手术患者在术中给予甲基强的松龙治疗有利于患者神经功能的恢复,是一种简单易行同时可以取得明显治疗效果的方式。Objective： To observe the clinical effect of methylprednisolone on patients with cervical spondilotic myelopathy.Method： 80 patients with cervical spondilotic myelopathy were selected and divided into two comparable groups randomly,the control group for 38 cases and the observation group for 42 cases.The control group received conventional operation,and the observation group were treated with methylprednisolone in operation on the basis of the control group.JOA score was applied to compare the joint function of two groups,and ODOM classification was used to evaluate the treatment effect of two groups.Result： After treatment,JOA score at 3 days,7 days,1month,3 months after operation for the patients in two groups were improved,but the observation group improved more evidently.And the outstanding rate and good rate of the observation group was respectively 19.05% and 80.95%,which was higher evidently than 13.16% and 44.74% of the control group.And the the above difference was evident,which had statistical significance（P 0.05）.Conclusion： Applying methylprednisolone for patients with cervical spondilotic myelopathy is good for the recovery of neurological function for patients,and it is a simple and practicable treatment which can achieve evident treatment effect.

关 键 词：颈椎病 脊髓型 甲基强的松龙 

分 类 号：R687.3[医药卫生—骨科学]