晚期早产儿263例患病情况临床分析  

Clinical analysis of primary diseases in 263 late preterm infants

作　　者：翁景文[1] 刘红[1] 董世霄[1] 靳绯[1] 刘靖媛[1] 

机构地区：[1]北京儿童医院新生儿中心,北京100045

出　　处：《山西医科大学学报》2013年第8期628-631,共4页Journal of Shanxi Medical University

摘　　要：目的分析晚期早产儿(late preterm infant,LPI)生后患病及并发症情况,分析需要呼吸支持治疗的围产期高危因素,为防治提供依据。方法分析263例晚期早产儿临床资料,用Logistic回归分析的方法筛选需要呼吸支持的晚期早产儿(LPI)的围产期高危因素,并分析常见临床并发症的发生情况。结果呼吸困难是LPI生后住院治疗的首要病因,原发病以湿肺(24.33%)和败血症(18.63%)为首,其各系统并发症的发病率均较高,以高胆红素血症(17.87%)、低血糖(13.68%)等为主。logistic回归显示双胎、妊高症、剖宫产及生后窒息是LPI需要呼吸支持的危险因素(均P<0.05)。结论 LPI生后易发生多种并发症,应注意观察,及时救治。重视围产期异常分娩因素,是降低LPI生后需要呼吸支持的关键。Objective To investigate the diseases and complications of late preterm infants（ LPI）, and to explore the perinatal risk fac- tors of LPI with the need of respiratory support. Methods The clinical data of 263 late pretenn infants were retrospectively analyzed. Multiple stepwise logistic regression method was used to assess the high risk factors of LPI with the need of respiratory support. The in- cidences of complications were recorded. Results Respiratory problem was the primary factor in treatment of LPI in hospital. The wet lung and sepsis were the top two primary diseases, with the incidence of 24.33 % and 18.63 % , respectively. LPI had higher incidences of complications than full term infant. The main complications were hyperbilirubinemia（ 17.87% ） and hypoglycemia（ 13.68% ）. Multi- ple stepwise logistic regression analysis showed twin birth, gestational hypertension, caesarean section and asphyxia were the risk factors for LPI with the need of respiratory support （ P 〈 0.05 ）. Conclusion LPI needs intensive monitoring after birth. Perinatal affairs play an important role to reduce the need of respiratory support.

关 键 词：晚期早产儿 呼吸支持 高危因素 

分 类 号：R722[医药卫生—儿科]