检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
出 处:《中国实验血液学杂志》2000年第2期145-148,共4页Journal of Experimental Hematology
摘 要:胚胎干细胞是体内各种组织包括造血组织干细胞的来源 ,在胚胎干细胞向造血干细胞的分化及造血干细胞自身的发育过程中有着复杂的基因调控。原始造血产生于卵黄囊已被普遍认可 ,但永久造血产生于何处仍有争论。目前认为 ,至少有两个独立的部位与永久造血有关 ,即卵黄囊和胚内的PAS/AGM区。对胚胎期造血及其调控的研究不仅有助于探明某些血液病的发病机制 。Stem cells of various tissues including hematopoietic tissue in the body are derived from embryonic stem cells (ESC).There exists intricated gene regulation during ESC development and its differentiation into hematopoietic stem cells (HSC). In embryo hematopoiesis development, there are two kinds of hematopoietic types, primitive hematopoiesis and definitive hematopoiesis. The theory of the yolk sac of primitive hematopoiesis is well accepted, while the initial site of definitive hematopoiesis still exists controversy. In present opinion, there are at least two independent sites associated with definitive hematopoiesis, those are, yolk sac and para aortic splanchnopleura (PAS)/aorta gonad mesonephros(AGM). Study on the hematopoiesis and its regulation during embryonic ontogeny will benefit not only to the dicovery of the mechanism of some blood disorders, but as well to gene therapy and HSC engineering.
分 类 号:R331.22[医药卫生—人体生理学]
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.200