前列腺癌患者调强放疗计划中不同算法计算结果分析  

Analysis of the Results Calculated from Different Algorithm in the IMRT Treatment Plan Design for Prostate Cancer Patients

作　　者：鞠永健[1] 王高仁[1] 曹丽媛[1] 李克新[1] 吴迪军[1] 汤娅红[1] 

机构地区：[1]江苏省南通市第一人民医院放疗科,江苏南通226001

出　　处：《中国辐射卫生》2013年第4期385-387,共3页Chinese Journal of Radiological Health

基　　金：国家自然科学基金(10705016);南通市社会事业科技创新与示范计划(S10964;HS2012036)

摘　　要：目的分析前列腺癌患者调强放疗计划设计时PBC和AAA算法计算得到的剂量学参数差异。方法对13例术后接受调强放射治疗的前列腺癌患者进行调强放疗计划设计时,分别用Eclipse Version 8.10治疗计划系统提供的PBC和AAA算法进行剂量计算并用二维电离室矩阵进行验证测量,比较两种算法获得的HI、CI、PTVDP、PTVmean、直肠和膀胱V50等参数差异,并将二维电离室矩阵测量的剂量分布与两种算法的计算结果分别进行比较获得γ通过率、单次照射时的DDmax及DDmean等参数差异。结果两种算法得到的靶区HI、CI、PTVDP、PTVmean平均相差分别为0.003、0.004、2.2%、10 cGy,直肠和膀胱V50值平均差异分别为0.3%和1.3%。γ通过率、DDmax及DDmean平均差异分别为0.9%、1.2%(2.4 cGy)和0.85%(1.7 cGy)。两种算法所获得的剂量学参数差异不大。结论对前列腺癌患者进行调强放疗计划设计时,PBC和AAA两种算法均可使用。Objective To analyze the dosimetric differences between the results calculated from the PBC algorithm and AAA algorithm respectively in the intensity -modulated radiotherapy（IMRT） treatment planning design for the prostate cancer patients. Methods For 13 postoperative prostate cancer patients, when the IMRT treatment plan was designed, the dose parameters were calculated with PBC algorithm and AAA algorithm respectively which was provided by the treatment plan-ning system（ Eclipse Version 8.10） , then the dosimetric parameters, such as HI,CI, PTVDp, PTV and the V50 of bladder and rectum were obtained and compared respectively. We also do the dose verification measurement with the two - dimensional ionization chamber array, and the actual measured dose distribution will be compared with that calculated from the AAA and PBC algorithm respectively to obtain the γ value, the dose difference in measurement chamber matrix point, DDmax and DDmean Results The average difference of HI, CI, PTVop and PTV between the results calculated with PBC and AAA algo-rithm separately are 0. 003,0. 004,2.2% ,10 cGy respectively, and the average difference of bladder V50 and rectum Vs0 are 0.3% and 1.3%. Compared the dosimetric result calculated from the above mentioned two algorithms with the measurement result, the average difference of γ value, DDmax and DD are 0.9%, 1.2% （2.4 cGy） and 0.85% （ 1.7 cGy） respectively. So the dose parameters calculated from the AAA and PBC algorithms are trivial. Conclusion For the prostate cancer patients IMRT treatment planning design, the PBC algorithm and AAA algorithm can all be used.

关 键 词：前列腺癌 PBC算法 AAA算法 放射疗法 

分 类 号：R144.1[医药卫生—公共卫生与预防医学]