基于四维CT图像的人体胸腔动态仿真模型研究进展  

Progresses of dynamic modeling and simulation of human thorax based on four-dimensional CT imaging

作　　者：罗洪艳[1] 张雨雯[1] 黄维[1] 张德燕[1] 文丽丽[1] 

机构地区：[1]重庆大学生物工程学院,重庆400044

出　　处：《中国介入影像与治疗学》2013年第9期571-574,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金：国家自然科学基金(60871099)

摘　　要：对于不适于手术治疗的胸腹腔肿瘤患者,个体化放疗是行之有效的治疗手段。基于CT、MRI的图像引导放射治疗(IGRT)和强调放射治疗(IMRT)可基本解决静止靶区的精确放疗问题,但对于胸腹腔内的运动靶区效果欠佳。基于四维CT(4D-CT)图像构建动态胸腔模型,可以准确真实反映人体胸腔内部器官和组织的运动情况,对实现个体化精确放疗有重要应用价值。本文对目前构建动态胸腔模型的主要方法及其研究进展进行综述。For patients thorax-abdominal tumor not suitable for surgery, personalized radiotherapy is an effective treatment. Image guided radiation therapy （IGRT） and the intensity modulated radiation therapy （IMRT） based on CT and MRI have almost solved the problems that involving the accurate radiotherapy for stationary targets. However, for moving targets such as thorax-abdominal tumors, the efficacy is still unsatisfactory. Construction of dynamic thorax-abdominal model based on four-dimensional CT images can provide a realistic phantom of internal motion organs, having great value in realizing accurate personalized radiotherapy. At present, researches at home and abroad have carried out studies on the dy- namic modeling and simulation of human thorax. The main aspects of relative technologies and progresses in this field were reviewed in this article.

关 键 词：四维计算机体层摄影术 动态模型 胸腔 仿真 

分 类 号：R811.5[医药卫生—放射医学]