聚醚醚酮/羟基磷灰石/碳纤维椎间融合器的有限元研究  

The Finite Element Analysis of Polyetheretherketone/Hydroxyapatite/Carbon Fiber Cage

作　　者：刘学勇[1] 朱洪欣[1] 荆延峰[1] 隋国鑫[2] 张宗富[3] 

机构地区：[1]中国医科大学附属盛京医院骨科,沈阳110004 [2]中国科学院金属研究所,沈阳110004 [3]暨南大学理工学院,广州510632

出　　处：《生物医学工程学杂志》2013年第4期873-878,共6页Journal of Biomedical Engineering

基　　金：沈阳市科学技术计划项目资助(F10-205-1-48)

摘　　要：对聚醚醚酮/羟基磷灰石/碳纤维(PEEK/HA/CF)和钛合金加椎弓根内固定两种类型的椎间融合器进行生物力学比较,为临床应用提供依据。基于人正常L2-L4节段的CT扫描数据,建立L2-L4节段和单枚融合器置入加椎弓根钉内固定有限元模型,观察不同工况下植骨块、椎间融合器和L3下终板的应力分布及融合节段的角位移变化。结果发现,PEEK/HA/CF组在植骨块的最大应力峰值至少是钛合金组的2.2倍;钛合金组在L3下终板的最大应力峰值至少是PEEK/HA/CF组的2.3倍,这些应力主要集中在与cage接触的终板部位;钛合金组的角位移与PEEK/HA/CF组相比较,其减少程度相当。因此,PEEK/HA/CF椎间融合器可以提供与钛合金相似的稳定性;增加植骨块的负荷传导,促进骨性融合;降低融合器毗邻终板的应力,降低融合器沉降。To compare the bio-mechanical characteristics of cages of two types,i.e.,polyetheretherketone/hydroxyapatite/carbon fiber（PEEK/HA/CF） and titanium combined with internal pedicle screw fixation in lumbar model,and to provide experimental evidences for clinical application,we constructed a three-dimensional finite element model of an intact L2-L4 segment by using computer tomography scans of a healthy male.The three-dimensional finite element models of an intact L2-L4 segment and single cage plus bilateral vertebral pedicle screw fixation were established.The angular motion of fused segment and stress distribution in the bone graft and cage and L3 inferior endplate under different loads were recorded.The result showed that the peak Von Mises stresses of the bone graft of PEEK/HA/CF group were at least 2.2 time as that of titanium group.The peak Von Mises stresses of L3 inferior endplate of the titanium group were at least 2.3 times as that of PEEK/HA/CF group.These stresses were concentrated at places where the cage interfaced with the endplate.The angular variation of the titanium group showed similarity to PEEK/HA/CF group.The PEEK/HA/CF cage could provide stability similar to that of titanium cage in the presence of posterior instrumentation.It could increase the load transfer through the bone graft and promote the bone fusion.It could also reduce the stresses in endplates adjacent to the cage and reduce the subsidence of the cage.

关 键 词：有限元分析 聚醚醚酮 羟基磷灰石 碳纤维 生物力学 

分 类 号：R687.3[医药卫生—骨科学]