短期铅接触工人外周血象的改变  

Changes in peripheral hemogram among workers with short-term lead exposure

作　　者：林晓娜[1] 谭夏优[1] 吴琳[1] 陈培仙[1] 

机构地区：[1]广州市职业病防治院,510620

出　　处：《中华劳动卫生职业病杂志》2013年第8期595-597,共3页Chinese Journal of Industrial Hygiene and Occupational Diseases

摘　　要：目的探讨短期职业性铅接触对工人血液中炎症反应系统的影响。方法以东莞某电子厂从事铅作业工龄≤1年的255名工人作为研究对象，选取另一工厂没有接触职业有害因素的205名管理人员作为对照组，进行职业健康检查以取得外周血象结果，并使用原子吸收光谱分析法测定血铅水平，用SPSS软件分析血铅与外周血象的关系。结果接触组的血铅值范围为0．07～1．70μmol／L，均在正常参考范围内。短期铅接触组白细胞计数、粒细胞百分比、粒细胞绝对值均高于对照组，校正年龄性别因素后，两组差异仍有统计学意义（P〈0．05）；而两组红细胞计数、血红蛋白值的差异无统计学意义（P〉0．05）。结论短期职业性铅接触可引起血液中炎症反应细胞的升高，但对红细胞和血红蛋白影响不明显。Objective To examine the effect of short-term occupational lead exposure on the inflammatory response system in blood among workers. Methods A total of 255 lead-exposed workers （length of service ≤ 1 year） at an electronics factory in Dongguan, China （exposure group）, as well as 205 managers without any occupational exposure at another factory （control group）, were included in the study. Occupational physical examination was done to get peripheral blood counts. The blood lead levels of workers were determined by atomic absorption spectrometry. The relationship between blood lead and peripheral hemogram was analyzed using SPSS software. Results The exposure group had blood lead levels of 0.07-1.70 μmol/L, falling within the normal range. The leukocyte count, percentage of granulocytes, and absolute value of granulocytes were significantly higher in the exposure group than in the control group, and the results remained unchanged after adjustment for age and sex （P〈0.05）. There were no significant differences in red blood cell count and hemoglobin value between the two groups （P〉0.05）. Conclusion Short-term occupational lead exposure may increase the counts of inflammatory cells in blood, but it has little effect on red blood cells and hemoglobin.

关 键 词：铅作业工人 短期接触 炎症反应细胞 

分 类 号：R131[医药卫生—劳动卫生]