BPH伴糖尿病患者尿流动力学观察及意义  

Observation of urodynamics in patients with benign prostatic hyperplasia complicated with diabetes mellitus

作　　者：徐郑[1] 贾瑞鹏[1] 朱佳庚[1] 苏江浩[1] 孙宏斌[1] 曹志刚[1] 

机构地区：[1]南京医科大学附属南京医院,南京210006

出　　处：《山东医药》2013年第31期13-15,共3页Shandong Medical Journal

基　　金：南京医科大学科技发展基金资助项目(2010NJMU060)

摘　　要：目的观察良性前列腺增生(BPH)伴糖尿病患者的尿流动力学特点。方法采用加拿大Laborie尿动力检查仪对78例BPH伴糖尿病患者(观察组)和80例单纯性BPH患者(对照组)进行尿流动力学检测,并比较两组检测结果。结果观察组膀胱初始尿意容量、最大膀胱容量、膀胱残余尿量、膀胱顺应性均明显高于对照组,最大逼尿肌压力明显低于对照组,两组比较,P均<0.05;观察组膀胱感觉减退者、高顺应性膀胱者、逼尿肌收缩乏力者所占比例均明显高于对照组(P均<0.05),膀胱出口梗阻者所占比例明显低于对照组(P<0.05)。结论当BPH合并糖尿病时,其典型的尿流动力学表现为膀胱感觉减退、顺应性增高、逼尿肌收缩乏力、膀胱容量及残余尿量增加,且膀胱逼尿肌受损较单纯性BPH患者更明显,治疗BPH合并糖尿病患者时,应积极控制血糖并及早手术解除膀胱出口梗阻,延缓膀胱逼尿肌功能的损害。Objective To observe the urodynamic features of patients with benign prostatic hyperplasia （BPH） complicated with diabetes mellitus. Methods The Canadian Laborie urodynamic instrument was used for urodynamic testing in 78 cases of BPH patients complicated with diabetes mellitus （ observation group） and 80 cases of simple BPH patients （control group）, and test results were compared. Results The first sensation, maximum bladder capacity, residual urine volume and bladder compliance in the observation group were significantly higher than those of the control group, but maximum detrusor pressure was significantly lower than that of the control group （ all P 〈 0.05 ） ; the proportion of impaired bladder sensation, high bladder compliance and detrusor underactivity in the observation group was higher than that of the control group （ all P 〈 0.05 ）, while the proportion of bladder outlet obstruction was significantly lower than that of the control group （P 〈 0.05 ）. Conclusions When BPH combined with diabetes, the typical urodynamic manifestations were bladder hypoesthesia, increased bladder compliance, detrusor contraction fatigue, and increased bladder capacity and residual urine volume, meanwhile the impaired detrusor was more obvious than that of the simple BPH patients. Therefore, we should actively control blood glucose, remove the bladder outlet obstruction early and delay detrusor function damage in the treatment of BPH patients with diabetes mellitus.

关 键 词：前列腺增生症 糖尿病 尿流动力学 

分 类 号：R691[医药卫生—泌尿科学] R587.1[医药卫生—外科学]